Products with Anticomplementary bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2159 | 1,2,3,6-Tetragalloylglucose |
| 1. 1,2,3,6-Tetragalloylglucose has antioxidative activity. 2. 1,2,3,6-Tetragalloylglucose shows the most potent anticomplement activity (IC(50), 34 microM). | |
| BCN2344 | Alisol A 24-acetate |
| Alisol A 24-acetate has antibacterial activity, it also has anti-complement activity against the classical pathway of the complement system with IC50 values of 130 microM. Alisol A 24-acetate can effectively prevent bone loss in ovariectomized (OVX) mice, and that it can be considered a potential therapeutic for the treatment of postmenopausal osteoporosis. | |
| BCN2941 | 6'-O-Galloyl paeoniflorin |
| 1. Galloylpaeoniflorin, gallic acid, paeoniflorin, and paeonol are the main effective components of Moutan Cortex, Moutan Cortex exhibits good activity on acute lung injury. 2. Galloylpaeoniflorin exhibits anticomplement effects. 3. Galloylpaeoniflorin reveals a more pronounced radical scavenging effect than a-tocopherol. 4. Galloylpaeoniflorin can take part in improving blood circulation by inhibiting ether platelet aggregation and/or blood coagulation. | |
| BCN3764 | Kansuiphorin C |
| 1. Kansuiphorin C shows cytotoxic activity. | |
| BCN3767 | 3-O-(2'E,4'Z-Decadienoyl)ingenol |
| 1. 20-O-(2′E,4′Z-decadienoyl)ingenol, one toxic terpenoid from raw Gansui. Kansuiphorin C and 3-O-(2′E,4′Z-decadienoyl)-ingenol exhibit significant anticomplement activity with respective 50% inhibitory concentration values of 44.1±3.8 and 89.5±5.5 uM. 2. 20-O-acetyl-[3-O-(2'E,4'Z)-decadienoyl]-ingenol and 3-O-(2'E,4'Z)-decadienoylingenol show the same antinematodal activity against the nematode, Bursaphelenchus xylophilus, at a minimum effective dose (MED) of 5 microg/cotton ball. | |
