Products with Antiviral bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5920 | Theaflavin 3,3'-di-O-gallate |
| Theaflavin-3,3'-digallate(TF3), an inducer of oxidative stress, which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregulating HIF-1αand VEGF; suggests that TF3 might serve as a potential anti-angiogenic agent for cancer treatment. TF3 and lactic acid combinations can reduce Herpes Simplex Virus(HSV) infectivity. | |
| BCN5941 | Glycyrrhizic acid |
| Glycyrrhizic acid has anti-tumor, antiviral ,antiallergic, anti-inflammatory, immunoregulatory,anti-diabetic activities. It is a direct HMGB1(high mobility group box 1) inhibitor that inhibits HMGB1-dependent inflammatory molecule expression and oxidative stress; modulates P38 and P-JNK but not p-ERK signalling; Also inhibits 11 beta-hydroxysteroid dehydrogenase and monoamine oxidase (MAO). | |
| BCN5956 | Fangchinoline |
| Fangchinoline is a nonspecific Ca2+ channel blocker, which has neuroprotective, antioxidant, anti-inflammatory, anti-cancer, vasodilating and hypotensive effects. It inhibited cell proliferation via Akt/GSK-3beta/ cyclin D1 signaling and induceed apoptosis in MDA-MB-231 breast cancer cells. It can inhibit human immunodeficiency virus type 1 replication by interfering with gp160 proteolytic processing. | |
| BCN5957 | Podophyllotoxin |
| Podophyllotoxin(Podofilox ) is a potent inhibitor of microtubule assembly and DNA topoisomerase II. Podophyllotoxin has antitumor and antiviral properties, but it also shows cytotoxicity for normal cells and hence side effects derived from its lack of selectivity against tumoral cells. | |
| BCN5971 | Sophocarpine |
| Sophocarpine has anti-cachectic, anti-inflammatory, and neuroprotective effects. It has significant antivirus effects against coxsackievirus B3 and therapeutic effects for viral myocarditis in clinical, can ameliorate the ischemic injury induced by transient focal cerebral ischemia in rats, and may be a potential chemotherapeutic agent for chronic liver diseases. Sophocarpine inhibited the expression of TNF-alpha, IL-6, JNK, iNOS, COX-2, p38 MAPK, NF-κB, TLR4, and activated signaling pathway of AMPK. | |
