Products with Immunosuppression bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3085 | Wilfortrine |
| Wilfortrine can induce liver cancer cell HepG2 apoptosis, but with no effect on the cell cycle, mainly by promoting Bax expression and inhibiting anti-apoptotic protein Bcl-2 expression. The combined treatment using wilfortrine and paclitaxel can inhibit proliferation and invasion of liver cancer cells via down-regulating Bcl-2 and up-regulating Bax, with better efficacy than single use of either drug. Wilfortrine and euonine (40.80 mg/(kg.d) x 4d ip) show marked depressant effects on humoral mediated immunity using the hemolysin reaction as indices. | |
| BCN3392 | Enmein |
| 1. Enmein shows significant inhibitory effect toward human tumor cell K562 with IC(50) values ranging from 3.2 microg/ml to 8.2 microg/ml. 2. Enmein has distinct immunosuppressive effect in vitro and in vivo systems, it depresses the murine ear swelling extent and the level of Interleukin-2 in blood serum in a dose-dependent manner. 3. Enmein shows antitumour activity against Ehrlich ascites carcinoma and is active against gram-positive bacteria. | |
| BCN3396 | Hypocrellin A |
| 1. Hypocrellin A , an a natural perylene quinine photosensitizers (PSs), can chelate with heavy metal ions, including Au(III) and Pt(IV), to form a 1:2 complex . 2. Hypocrellin A has light-induced antitumor activity . 3. Hypocrellin A has antifungal and antiviral activities. 4. Hypocrellin A exerts immunomodulatory effects on MHC-restricted presentation of antigen. | |
| BCN3445 | Hopeachinol B |
| 1. Hopeachinol B is a potent immunosuppressive polyphenol. | |
| BCN3876 | Perillyl alcohol |
| Perillyl alcohol has potential chemopreventive, and antileukemia activities, it can suppress antigen-induced immune responses in the lung, it could be a novel preventive or therapeutic option for immunologic lung disorders such as asthma with minimal side effects. Perillyl alcohol can suppress antigen-induced immune responses in the lung, it could be a novel preventive or therapeutic option for immunologic lung disorders such as asthma with minimal side effects. | |
