Products with Microtubule stabilizers bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2737 | Taccalonolide A |
| Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is the first natural product steroid identified to have these cellular effects. | |
| BCN2743 | Taccalonolide B |
| Taccalonolide B displays microtubule stabilizing activity.Several taccalonolides have in vitro antitrypanosomal activity against Trypanosoma brucei brucei and EC50 values for the isolated compounds were from 0.79 ug/mL. | |
| BCN2971 | Taccalonolide AJ |
| Taccalonolide AJ is a microtubule stabilizer; it has excellent and highly persistent antitumor efficacy when administered directly to the tumor, suggesting that the lack of antitumor efficacy seen with systemic administration of AJ is likely due to its short half-life in vivo. | |
