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Natural Products from Aquilegia oxysepala

Natural Products Isolated from Aquilegia oxysepala

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  • Broad structural diversity and coverage of biological activities.
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Natural Products from Aquilegia oxysepala

4 natural product s associated with Aquilegia oxysepala

Natural products and bioactive compounds from Aquilegia oxysepala
Catalog No. Product Name CAS Number COA
BCN5488 Genkwanin
Genkwanin chemical structure
437-64-9 COA
BCN7845 Isoscoparin
Isoscoparin chemical structure
20013-23-4 COA
BCN4985 Luteolin-6-C-glucoside
Luteolin-6-C-glucoside chemical structure
4261-42-1 COA
BCN5890 Succinic acid
Succinic acid chemical structure
110-15-6 COA

References

Validate antibacterial mode and find main bioactive components of traditional Chinese medicine Aquilegia oxysepala.[Pubmed: 17276058]


Traditional Chinese medicines have been used for thousands of years and are still being used as one of the regular treatments for many diseases. However, their mechanisms were still unknown. In this investigation, a possible procedure combining metabonomics and principal component analysis to investigate antibacterial modes of action and find main antimicrobial component in traditional Chinese medicine, Aquilegia oxysepala, is developed. Metabolic profiles of Staphylococcus aureus treated with nine antibiotics of known modes of action and with A. oxysepala were acquired by HPLC/DAD/ESI-MS. After statistical processing by principal components analysis on metabolic profiles, two conclusions could be drawn: (1) the target of A. oxysepala may be similar to that of lincolmensin, erythromycin, chloromycetin, streptomycin, and acheomycin, whose targets are protein; (2) its bioactive component playing main antimicrobial roles on S. aureus may be maguoflorine.