Callicarpa kochiana
Callicarpa kochiana
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Natural products/compounds from Callicarpa kochiana
- Cat.No. Product Name CAS Number COA
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BCN4327
Ursolic acid77-52-1
Instructions
Two new abietane diterpenoids from the caulis and leaves of Callicarpa kochiana.[Pubmed: 21983345]
Previous studies revealed that diterpenoids from Callicarpa genus were mainly of clerodane-type and phyllocladane-type, and abietane-type diterpenoids were seldom reported. In this paper, we reported two new abietane diterpenoids, kochianic acid A (1) and kochianic acid B (2), together with two known abietane-type diterpenoids, pedunculatic acid B (3) and 7α, 15-dihydroxydehydroabietic acid (4), which were all isolated from Callicarpa kochiana. The structures of the new compounds 1 and 2 were elucidated on the basis of extensive spectroscopic analysis, including HSQC, HMBC, (1)H-(1)H COSY, ROESY and finally confirmed by single-crystal X-ray diffraction.
[Studies on the chemical constituents of Callicarpa kochiana].[Pubmed: 21049609]
To study on the chemical constituents of Callicarpa kochiana.
[Effect of Callicarpa herbs on antioxidation in vitro].[Pubmed: 12575098]
The concentration of half inhibition (IC50) of Callicarpa herbs, including Callicarpa kochiana(Ck), C. bodinieri (Cb) and its fruit (Cbf), C. japonica, C. macrophrlla, C. cathaarana, C. giraldi(Cg) on lipid peroxidation (LPO) of tissus homogenate incubated in 37 +/- 0.5 degrees C were tested. The result showed that all but Cg could inhibit lipid peroxidation. The IC50 of Cbf was minimum. IC50 of Cb, Cbf and Ck inhibiting red blood cell (RBC) LPO and hemolysis caused by hydroxyl free radical (.OH), inhibiting brain homogenate LPO induced by .OH and inhibiting or clean .OH formation by system of H2O2 and FeSO4 were also tested. It was found the IC50 were Cbf > Cb > Ck. These results suggested that the most strong inhibitor to automatic LPO reaction was Cbf, but to LPO caused by .OH was Ck.
