Natural Products from Calophyllum membranaceum
Natural Products Isolated from Calophyllum membranaceum
BioCrick provides high-purity natural products and bioactive compounds isolated and purified from natural sources for scientific research.
- Natural product compounds selected from diverse chemical and biological sources.
- Broad structural diversity and coverage of biological activities.
- Product activity information can be supported by published literature, patents and research reports.
- Natural products can be selected according to source, target, activity and disease research interests.
- Compounds should be stored according to the product specifications after receipt.
Natural Products from Calophyllum membranaceum
4 natural product s associated with Calophyllum membranaceum
| Catalog No. | Product Name | CAS Number | COA |
|---|---|---|---|
| BCN6283 |
Amentoflavone
|
1617-53-4 | COA |
| BCN3617 |
Ammijin
|
495-30-7 | COA |
| BCN5604 |
Nodakenetin
|
495-32-9 | COA |
| BCN2378 |
Nodakenin
|
495-31-8 | COA |
References
C-glycosides from the stems of Calophyllum membranaceum.[Pubmed: 29210296]
Three new C-glycosides, calophymembransides D-F (1-3), were isolated from the stems of Calophyllum membranaceum Gardn. et Champ.. The structures were assigned on the basis of spectroscopic data. RXRα transcriptional inhibition and α-glucosidase inhibition assays indicated that all the isolates were inactive.
RXRα transcriptional inhibitors from the stems of Calophyllum membranaceum.[Pubmed: 26569353]
Bioassay-guided fractionation of the 60% ethanol extract of the stems of Calophyllum membranaceum using the RXRα transcription activation assay led to the isolation of two new chromanones, calopolyanic acid methyl ester (1) and isopinetoric acid methyl ester (2), two new xanthones, calophylixanthones A-B (3-4), and one new C-glycoside, calophymembranside C (5), along with 13 known compounds. Their structures were elucidated on the basis of extensive spectroscopic data. Compounds 5, 11 and 18 showed transcriptional inhibitory activity of RXRα with 50% inhibitory concentration (IC50) values of 29.95 ± 1.08, 31.06 ± 9.02, and 25.88 ± 1.62 μM, respectively.
2-Hydr-oxy-1-methoxyxanthen-9-one monohydrate.[Pubmed: 21578390]
In the title compound, C(14)H(10)O(4)·H(2)O, isolated from the roots of Calophyllum membranaceum, the xanthene ring system is almost planar (r.m.s. deviation = 0.008 Å). In the crystal structure, inter-molecular O-H⋯O and O-H⋯(O,O) hydrogen bonds connect the mol-ecules.
Selective cyclooxygenase-2 inhibitors from Calophyllum membranaceum.[Pubmed: 16252917]
Chemical investigation of the anti-inflammatory Chinese folk medicine Calophyllum membranaceum has resulted in the isolation and characterization of three new xanthones (1-3), one new biphenyl C-glycoside (4), and one new phenylethanoid glycoside (5) along with 17 known compounds. Their structures were characterized on the basis of spectroscopic and chemical methods. Two xanthones, 2,6-dihydroxy-1,7-dimethoxyxanthone (1) and 3,4-dihydroxyxanthone, were found to exhibit selective inhibitory activity against cyclooxygenase-2 (IC(50)=2.99 and 1.80 microM) in vitro.