Litsea pedunculata
Litsea pedunculata
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Natural products/compounds from Litsea pedunculata
- Cat.No. Product Name CAS Number COA
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BCN5528
Betulin473-98-3
Instructions
Novel cytotoxic chalcones from Litsea rubescens and Litsea pedunculata.[Pubmed: 22047698]
Two novel flavonoids with chalcone skeleton, together with seven known flavonoids, were isolated from the stem barks of Litsea rubescens and Litsea pedunculata. The structures of the new compounds were elucidated on the basis of spectral methods including IR, UV, 1D and 2D NMR. The new chalcones were found to contain the rare epoxy or ethylidenedioxy group. This is the first report on the presence of chalcone in the plant genus Litsea. The cytotoxic potential of two new chalcones was evaluated in vitro against three human tumor cell lines. Both new chalcones displayed potent cytotoxic activities against myeloid leukaemia (HL-60) and epidermoid carcinoma (A431) cell lines and more active than cisplatin (DDP). Interestingly, compound 1 exhibited cytotoxic activity against HL-60 with IC(50) value 2.1-fold more sensitive to DDP.
A novel aryltetralone lignan from Litsea pedunculata.[Pubmed: 20183272]
A novel aryltetralone lignan, pedunculine A (1), together with a known lignan cagayanone A (2), was isolated from the leaves and twigs of Litsea pedunculata. The structure of the new lignan was elucidated on the basis of spectroscopic methods and single-crystal X-ray diffraction.
