Natural Products from Potentilla kleiniana

Natural Products Isolated from Potentilla kleiniana

BioCrick provides high-purity natural products and bioactive compounds isolated and purified from natural sources for scientific research.

  • Natural product compounds selected from diverse chemical and biological sources.
  • Broad structural diversity and coverage of biological activities.
  • Product activity information can be supported by published literature, patents and research reports.
  • Natural products can be selected according to source, target, activity and disease research interests.
  • Compounds should be stored according to the product specifications after receipt.

Natural Products from Potentilla kleiniana

1 natural product associated with Potentilla kleiniana

Natural products and bioactive compounds from Potentilla kleiniana
Catalog No. Product Name CAS Number COA
BCN4327 Ursolic acid
Ursolic acid chemical structure
77-52-1 COA

References

Antihyperglycemic and antioxidant effect of the total flavones of Potentilla kleiniana Wight et Arn. in streptozotocin induced diabetic rats.[Pubmed: 28603128]


To investigate the antihyperglycemic and antioxidant activity of the total flavones of Potentilla kleiniana Wight et Arn. (TFP) in streptozotocin (STZ) induced diabetic rats. STZ-induced diabetic rats were treated with TFP weekly for 4 weeks at three doses (100 mg/kg, 200 mg/kg and 400 mg/kg). Blood glucose levels (BGL), body weight, insulin, total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL), very low density lipoprotein (VLDL), low density lipoprotein (LDL), malondialdehyde (MDA), glutathione (GSH), super oxide dismutase (SOD) and catalase (CAT) levels of liver and pancreas were measured weekly for 4 weeks. STZ administration resulted in oxidative damage of pancreas, then hyperglycemia proved by higher MDA, lower insulin and higher BGL in comparison to normal rats. TC, TG, LDL and VLDL cholesterol levels were also significantly elevated with decreased GSH, SOD, and CAT levels. A steady decrease in BGL and increase in insulin level were observed 4 weeks after TFP treatment in a dose dependent manner, as well as remarkable improvement in body weight and biochemical parameters. TFP have the effect of inhibiting hyperglycemia and oxidative stress, and the administration may be helpful in the prevention of diabetic complications associated with oxidative stress.