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Natural Products from Pouzolzia zeylanica var. microphylla

Natural Products Isolated from Pouzolzia zeylanica var. microphylla

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Natural Products from Pouzolzia zeylanica var. microphylla

2 natural product s associated with Pouzolzia zeylanica var. microphylla

Natural products and bioactive compounds from Pouzolzia zeylanica var. microphylla
Catalog No. Product Name CAS Number COA
BCN1104 Epifriedelanol
Epifriedelanol chemical structure
16844-71-6 COA
BCN4376 Stigmasterol
Stigmasterol chemical structure
83-48-7 COA

References

Norlignans from Pouzolzia zeylanica var. microphylla and their nitric oxide inhibitory activity.[Pubmed: 26067593]


Five new compounds, pouzolignan F [4-hydroxy-3-(3,5-dihydroxyphenyl)-2-[bis(4-hydroxy-3-methoxyphenyl)methyl]butyl acetate] (1), pouzolignan G [4-hydroxy-3-(3,5-dihydroxyphenyl)-2-[(4-hydroxy-3,5-dimethoxyphenyl)(4-hydroxy-3-methoxyphenyl)methyl]butyl acetate] (2), pouzolignan H [1,4-dihydroxy-3-(3,5-dihydroxyphenyl)-2-[bis(4-hydroxy-3-methoxyphenyl)methyl]butane] (3), pouzolignan I [1,4-dihydroxy-3-(3,5-dihydroxyphenyl)-2-[(4-hydroxy-3,5-dime thoxyphenyl)-(4-hydroxy-3-methoxyphenyl)methyl]butane] (4), and pouzolignan J [1,4-dihydroxy-3-(3,5-dihydroxyphenyl) -2-[(3,4,5-trimethoxyphenyl)(4-hydroxy-3-methoxyphenyl)methyl]butane] (5), along with two known compounds, indolyl-3-carboxylic acid (6) and uracil (7), were isolated from the aerial parts of Pouzolzia zeylanica (L.) Benn. var. microphylla (Wedd.) W.T.Wang. The structures of these compounds were characterized based on spectroscopic methods, including IR, NMR ((1)H-(1)H COSY, HSQC, HMBC, and NOESY), and HR-ESI/TOF-MS experiments. All the new norlignans were assayed for inhibitory activity against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in mouse peritoneal macrophages.