Natural Products from Swertia cincta
Natural Products Isolated from Swertia cincta
BioCrick provides high-purity natural products and bioactive compounds isolated and purified from natural sources for scientific research.
- Natural product compounds selected from diverse chemical and biological sources.
- Broad structural diversity and coverage of biological activities.
- Product activity information can be supported by published literature, patents and research reports.
- Natural products can be selected according to source, target, activity and disease research interests.
- Compounds should be stored according to the product specifications after receipt.
Natural Products from Swertia cincta
7 natural product s associated with Swertia cincta
| Catalog No. | Product Name | CAS Number | COA |
|---|---|---|---|
| BCN2814 |
6'-O-beta-D-Glucosylgentiopicroside
|
115713-06-9 | COA |
| BCN5487 |
Crategolic acid
|
4373-41-5 | COA |
| BCN4909 |
Gentiopicroside
|
20831-76-9 | COA |
| BCN5057 |
Loganic acid
|
22255-40-9 | COA |
| BCN6219 |
Sweroside
|
14215-86-2 | COA |
| BCN1116 |
Swertiamarin
|
17388-39-5 | COA |
| BCN2759 |
Swertianolin
|
23445-00-3 | COA |
References
Analyzing the hepatoprotective effect of the Swertia cincta Burkillextract against ANIT-induced cholestasis in rats by modulating the expression of transporters and metabolic enzymes.[Pubmed: 28734962]
Swertia cincta Burkill was traditionally used for treating jaundice and various types of chronic and acute hepatitis in Yunnan and Tibet in China for hundreds of years. This study aims to investigate the protective effect of S. cincta Burkill (ESC) extract on alpha-naphthylisothiocyanate (ANIT)-induced hepatotoxicity and cholestasis in rats.
Five new secoiridoid glycosides and one unusual lactonic enol ketone with anti-HBV activity from Swertia cincta.[Pubmed: 25721422]
Five new secoiridoid glycosides, swericinctosides A and B (1-2), 9-epi swertiamarin (3), 2'-O-m-hydroxybenzoyl swertiamarin (4), 4″-O-acetyl swertianoside E (5), and one unusual lactonic enol ketone, 3-(hydroxymethyl ene) dihydro-2H-pyran-2, 4(3H)-dione (6), together with three known compounds, swertiaside (7), swertianoside C (8) and decentapicrin B (9) were isolated from Swertia cincta. The structures of the new compounds were determined by extensive spectroscopic analyses including 1D and 2D NMR, HRESIMS, UV, IR and [α]D spectra. Anti-HBV assay on HepG 2.2.15 cell line in vitro demonstrated that compounds 1-9 possessed inhibitory activity on HBV DNA replication with IC50 values from 0.05 to 1.83mM, and compounds 1, 3, 5, 7 and 8 could inhibit the secretion of HBsAg with IC50 values from 0.24 to 1.06mM.