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Swertia leducii

Swertia leducii

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Natural products/compounds from  Swertia leducii

  1. Cat.No. Product Name CAS Number COA
  2. BCN5487 Crategolic acid4373-41-5 Instructions

References

LC-MS guided isolation of (±)-sweriledugenin A, a pair of enantiomeric lactones, from Swertia leducii.[Pubmed: 24359182]


(±)-Sweriledugenin A, a pair of novel enantiomeric lactones, were isolated from Swertia leducii under the guidance of LC-MS investigation. The enantiomeric separation was achieved by HPLC on a chiral column. Their structures were determined by extensive NMR spectra, X-ray, and quantum calculations. (+)-Sweriledugenin A and (-)-sweriledugenin A showed activities inhibiting HBV DNA replication with the IC50 values of 36.86 and 26.55 μM on the HepG 2.2.15 cell line in vitro.