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Swertia patens

Swertia patens

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Natural products/compounds from  Swertia patens

  1. Cat.No. Product Name CAS Number COA
  2. BCN2661 Amarogentin21018-84-8 Instructions

References

Two new secoiridoids and other anti-hepatitis B virus active constituents from Swertia patens.[Pubmed: 26727588]


Two new secoiridoids, swerpatic acid (1) with an unusual C8 skeleton and swerpalactone (2), were isolated along with ten known compounds (3-12) from the whole plants of Swertia patens. Their structures were elucidated by comprehensive spectroscopic analyses. Eight compounds were evaluated for their anti-hepatitis B virus (HBV) activities on Hep G 2.2.15 cell line in vitro. Compounds 4 and 10 showed moderate inhibitory activities on the secretion of HBsAg with IC50 values of 1.96 and 0.50 mM.