Ganoderic acid D

Catalog No.	BCN2437
CAS RN	108340-60-9
Molecular Weight	514.66
Molecular Formula	C30H42O7
Database	[PubChem]:382153146 [ChEBI]: [PCIDB]:23823

Definition

Standard InChI

InChI=1S/C30H42O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h15-16,18-19,21,32H,8-14H2,1-7H3,(H,36,37)/t15-,16?,18-,19+,21?,28+,29-,30+/m1/s1

Biological Activity

Ganoderic acid D (GD) is the major active triterpenoid in Ganoderma lucidum, a medicinal fungus used daily; biliary rather than renal clearance was the major route of excretion, the metabolic transformation included reduction, monohydroxylation, dihydroxylation, trihydroxylation, oxidation, desaturation, sulfation, and glucuronidation; the main metabolic soft spots in the chemical structure of GD were the 3-carbonyl group, angular methyl groups, the 7-hydroxy group, and the 26-carboxylic acid moiety.[1]

Product information

English website: Ganoderic acid D
Japanese website: Ganoderic acid D
Chinese website: Ganoderic acid D

References

[1] Cheng C, Yang M, Yu K, et al. Drug Metab Dispos , 2012, 40(12):2307-14.
[2] Zhao J, Chen X, Kaishun B I. China j Chinese Materia Med, 2009, 34(17):2220-2.