Isomahanine

Catalog No.	BCN3177
CAS RN	144606-95-1
Molecular Weight	347.5
Molecular Formula	C23H25NO2
Database	[PubChem]:382155979 [ChEBI]: [PCIDB]:24713

Definition

Standard InChI

InChI=1S/C23H25NO2/c1-14(2)6-5-10-23(4)11-9-17-21(26-23)8-7-16-18-12-15(3)20(25)13-19(18)24-22(16)17/h6-9,11-13,24-25H,5,10H2,1-4H3

Biological Activity

Isomahanine and mahanine , isolated from the ethyl acetate extract of Murraya koenegii (Rutaceae) leaves, show antibacterial activity towards Flavobacterium columnare and Streptococcus iniae which caused columnaris disease and streptococcosis respectively; isomahanine has the strongest activity against F. columnare (isolate ALM-00-173) and S. iniae (isolate LA94-426) based on 24-h 50% inhibition concentration (IC50) and minimum inhibition concentration (MIC). [1]
Isomahanine is a potent inhibitor of sEH , with IC50 values of 22.565±651.7 . [2]

Product information

English website: Isomahanine
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Chinese website: Isomahanine

References

[1] Meepagala K M, Schrader K K, Burandt C L. J Agr Chem Env, 2013, 02(4):90-100.
[2] Kim J H, Morgan A M, Tai B H, et al. J Enzym Inhib Med Ch, 2015:1-5.