The glycosyloxyflavone which is the 7-O-glucuronide of baicalein.
Baicalin is a flavonoid and a major component of a herbal medicine, Sho-saiko-to, which is commonly used for treatment of chronic hepatitis in Japan and China. baicalin acts as anti-oxidants, also causes cytotoxic effect,and induces caspase-3 activation and apoptosis via mitochondrial pathway.[1]
Baicalin has anti-inflammatory activity, exhibits the greatest inhibition activity against carrageenan-induced rat paw edema.[2]
Baicalin has neuroprotection, might be associated with its anti-oxidative and anti-apoptotic properties in global cerebral ischemia in the gerbils.[3]
[1] Ueda S, Nakamura H, Masutani H, et al. Mol Immunol, 2002, 38(10):781-91.
[2] Chun-ChingLin, Den-EnShieh. Am J Chinese Med , 1996, 24(1):31-6.
[3] Cao Y, Mao X, Sun C, et al. Brain Res Bull , 2011, 85(6):396-402.
[4] Yu-Xiang G U, Zhou Z L, Yang Y M, et al. Physical Testing & Chemical Analysis, 2012(4).
