InChI=1S/C16H18O9/c17-9-3-1-8(5-10(9)18)2-4-13(20)25-12-7-16(24,15(22)23)6-11(19)14(12)21/h1-5,11-12,14,17-19,21,24H,6-7H2,(H,22,23)/b4-2+/t11-,12-,14-,16+/m1/s1
Chlorogenic acid, a phenolic compound found ubiquitously in plants, is an in vitro antioxidant and metal chelator, some derivatives of chlorogenic acid are hypoglycemic agents and may affect lipid metabolism;in vivo, chlorogenic acid can improve glucose tolerance, decrease some plasma and liver lipids, and improve mineral pool distribution.[1]
Chlorogenic acid and caffeic acid have antioxidant property, have effects on intestinal ischemia–reperfusion injury.[2]
Chlorogenic acid has antiviral activity, reduces serum DHBV level in DHBV-infected duckling model, shows inhibitory effect on HBV replication.[3]
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[1] Sotillo D V R D, Hadley M. J Nutr Biochem, 2002, 13(12):717-726.
[2] Sato Y, Itagaki S, Kurokawa T, et al.Int J Pharm, 2011, 403(1-2):136-138.
[3] Wang G F, Shi L P, Ren Y D, et al. Antivir Res, 2009, 83(2):186-90.
[4] Li X P, Yu J, Luo J Y, et al.Biomed Chromatogr, 2006, 20(2):206-10.
