Cimifugin

Catalog No. BCN5433
CAS RN 37921-38-3
Molecular Weight 306.3
Molecular Formula C16H18O6
Database [PubChem]:382160545
[ChEBI]:3701
[PCIDB]:2421

Definition

Standard InChI

InChI=1S/C16H18O6/c1-16(2,19)13-5-9-11(22-13)6-12-14(15(9)20-3)10(18)4-8(7-17)21-12/h4,6,13,17,19H,5,7H2,1-3H3/t13-/m0/s1

Biological Activity

Cimifugin, isolated from Peucedanum schottii, displays low to moderate inhibition towards AChE and BChE (3.12 and 21.63%, respectively) at 200 µg mL-1.[1]
Cimifugin evidently inhibits FITC-induced type 2 allergic contact dermatitis,and its mechanism might related to regulating the balance of Th1 /Th2 by inhibiting type 2 cytokines.[2]

Product information

English website: Cimifugin
Japanese website: Cimifugin
Chinese website: Cimifugin

References

[1] Koziol E, Senol F S, Orhan I E, et al. Natl Prod Communicat, 2016, 6.
[2] Jiang X, Wang H, Gui L, et al. Pharmacol Clin Chinese Mat Med, 2014, 30(2):28-30.
[3] Wang X, Wang Z, Sun H, et al. Arzneimittel-Forschung, 2008, 58(9):445-50.