A triterpenoid saponin that is cycloastragenol with a 2-O-β-D-glucopyranosyl-β-D-xylopyranosyl moiety attached at position 3 via a glycosidic linkage.
Astragaloside III can effectively reduce cancer cell survival in vitro and inhibit the tumor growth in vivo, the potential mechanism is the induction of cell apoptosis signaling pathways, suggests that it provides a new therapeutic tool to treat breast cancer.[1]
AstragalosideIII, ononin and astragalosideIV have anti-gastric ulcer effects, also exhibit strong growth-promoting effects in cultured GES-1 cells.[2]
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[1] Wang S, Tang L, Chen F. Afr J Tradit Complem, 2015, 12(3):183-6.
[2] Liu X H, Zhao L G, Liang J, et al. J Chromatogr B , 2014, 960(6):43-51.
[3] Wang H, Wang Q. J Chinese Pharm Sci, 2002, 37(4):298-300.