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(1S,2S)-threo-Honokitriol

CAS# 1099687-80-5

(1S,2S)-threo-Honokitriol

2D Structure

Catalog No. BCN8644----Order now to get a substantial discount!

Product Name & Size Price Stock
(1S,2S)-threo-Honokitriol: 5mg Please Inquire In Stock
(1S,2S)-threo-Honokitriol: 10mg Please Inquire In Stock
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(1S,2S)-threo-Honokitriol: 500mg Please Inquire Please Inquire
(1S,2S)-threo-Honokitriol: 1000mg Please Inquire Please Inquire

Quality Control of (1S,2S)-threo-Honokitriol

3D structure

Package In Stock

(1S,2S)-threo-Honokitriol

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Chemical Properties of (1S,2S)-threo-Honokitriol

Cas No. 1099687-80-5 SDF Download SDF
PubChem ID 25209869 Appearance Powder
Formula C18H20O5 M.Wt 316.4
Type of Compound Lignans Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1S,2S)-1-[4-hydroxy-3-(4-hydroxy-3-prop-2-enylphenyl)phenyl]propane-1,2,3-triol
SMILES C=CCC1=C(C=CC(=C1)C2=C(C=CC(=C2)C(C(CO)O)O)O)O
Standard InChIKey LKYOLPWSGNGKSH-ROUUACIJSA-N
Standard InChI InChI=1S/C18H20O5/c1-2-3-12-8-11(4-6-15(12)20)14-9-13(5-7-16(14)21)18(23)17(22)10-19/h2,4-9,17-23H,1,3,10H2/t17-,18-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of (1S,2S)-threo-Honokitriol

The barks of Magnolia officinalis

Biological Activity of (1S,2S)-threo-Honokitriol

In vitro

Phenolic Constituents from the Stem Bark of Magnolia officinalis.[Reference: WebLink]

Journal of Natural Products, 2009, 72(1):168-171.


METHODS AND RESULTS:
Three new compounds, magnolianone (1), erythro-honokitriol (2), and threo-honokitriol (3), together with 14 known compounds, magnaldehyde (4), magnatriol B (5), randaiol (6), obovatol (7), magnolignan B (8a and 8b), magnolol, honokiol (9), p-hydroxylbenzaldehyde, coniferaldehyde, coniferol alcohol, syringaldehyde, syringaresinol, and acteoside, were isolated from the MeOH-soluble part of a water extract of the stem bark of Magnolia officinalis.
CONCLUSIONS:
Among these compounds, 2-8b were studied for anti-inflammatory and antioxidative activities. Compound 7 displayed more potent antioxidative potential than 9. Compounds 4-7 effectively inhibited LPS-induced NO production, whereas 5 and 6 were more potent than 9.

(1S,2S)-threo-Honokitriol Dilution Calculator

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(1S,2S)-threo-Honokitriol Molarity Calculator

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Preparing Stock Solutions of (1S,2S)-threo-Honokitriol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1606 mL 15.8028 mL 31.6056 mL 63.2111 mL 79.0139 mL
5 mM 0.6321 mL 3.1606 mL 6.3211 mL 12.6422 mL 15.8028 mL
10 mM 0.3161 mL 1.5803 mL 3.1606 mL 6.3211 mL 7.9014 mL
50 mM 0.0632 mL 0.3161 mL 0.6321 mL 1.2642 mL 1.5803 mL
100 mM 0.0316 mL 0.158 mL 0.3161 mL 0.6321 mL 0.7901 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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