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11alpha-Methoxysaikosaponin F

CAS# 104109-37-7

11alpha-Methoxysaikosaponin F

Catalog No. BCN8653----Order now to get a substantial discount!

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11alpha-Methoxysaikosaponin F: 5mg Please Inquire In Stock
11alpha-Methoxysaikosaponin F: 10mg Please Inquire In Stock
11alpha-Methoxysaikosaponin F: 20mg Please Inquire Please Inquire
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Quality Control of 11alpha-Methoxysaikosaponin F

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Chemical structure

11alpha-Methoxysaikosaponin F

3D structure

Chemical Properties of 11alpha-Methoxysaikosaponin F

Cas No. 104109-37-7 SDF Download SDF
PubChem ID 21637637 Appearance Powder
Formula C49H82O18 M.Wt 959.17
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S,3R,4R,5R,6S)-2-[(2R,3S,4R,5R,6R)-6-[[(3S,4aR,6aR,6bS,8S,8aS,12aS,14R,14aR,14bS)-8-hydroxy-8a-(hydroxymethyl)-14-methoxy-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-4,5-dihydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-3-yl]oxy-6-methyloxane-3,4,5-triol
SMILES CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3CCC4(C(C3(C)C)CCC5(C4C(C=C6C5(CC(C7(C6CC(CC7)(C)C)CO)O)C)OC)C)C)COC8C(C(C(C(O8)CO)O)O)O)O)O)O
Standard InChIKey QUBQEHLOFWDOPC-OZRHACRWSA-N
Standard InChI InChI=1S/C49H82O18/c1-22-31(53)33(55)37(59)42(63-22)67-39-27(20-62-41-36(58)34(56)32(54)26(19-50)64-41)65-43(38(60)35(39)57)66-30-11-12-46(6)28(45(30,4)5)10-13-47(7)40(46)25(61-9)16-23-24-17-44(2,3)14-15-49(24,21-51)29(52)18-48(23,47)8/h16,22,24-43,50-60H,10-15,17-21H2,1-9H3/t22-,24-,25+,26+,27+,28-,29-,30-,31-,32+,33+,34-,35+,36+,37+,38+,39+,40+,41+,42-,43-,46-,47+,48+,49+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 11alpha-Methoxysaikosaponin F

The herbs of Bupleurum chinense DC.

11alpha-Methoxysaikosaponin F Dilution Calculator

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11alpha-Methoxysaikosaponin F Molarity Calculator

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Preparing Stock Solutions of 11alpha-Methoxysaikosaponin F

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0426 mL 5.2128 mL 10.4257 mL 20.8514 mL 26.0642 mL
5 mM 0.2085 mL 1.0426 mL 2.0851 mL 4.1703 mL 5.2128 mL
10 mM 0.1043 mL 0.5213 mL 1.0426 mL 2.0851 mL 2.6064 mL
50 mM 0.0209 mL 0.1043 mL 0.2085 mL 0.417 mL 0.5213 mL
100 mM 0.0104 mL 0.0521 mL 0.1043 mL 0.2085 mL 0.2606 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Description

11(α)-Methoxysaikosaponin F is a triterpenoid saponin isolated from Bupleurum marginatum Wall.ex DC(ZYCH) which is a promising therapeutic for liver fibrosis. 11(α)-Methoxysaikosaponin F has an IC50 of 387.7 nM with viability of hepatic stellate cells-T6 (HSCs-T6). Triterpenoid saponins have numerous targets, important network positions, and strong inhibitory activity.

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