4-DemethyltraxillasideCAS# 1691201-82-7 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
| Cas No. | 1691201-82-7 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C27H34O12 | M.Wt | 550.6 |
| Type of Compound | Lignans | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
4-Demethyltraxillaside Dilution Calculator
4-Demethyltraxillaside Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.8162 mL | 9.081 mL | 18.162 mL | 36.324 mL | 45.405 mL |
| 5 mM | 0.3632 mL | 1.8162 mL | 3.6324 mL | 7.2648 mL | 9.081 mL |
| 10 mM | 0.1816 mL | 0.9081 mL | 1.8162 mL | 3.6324 mL | 4.5405 mL |
| 50 mM | 0.0363 mL | 0.1816 mL | 0.3632 mL | 0.7265 mL | 0.9081 mL |
| 100 mM | 0.0182 mL | 0.0908 mL | 0.1816 mL | 0.3632 mL | 0.4541 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Sepiumol E
Catalog No.:BCN9265
CAS No.:2412027-09-7
- Juncuenin A
Catalog No.:BCN9264
CAS No.:1161681-18-0
- Juncuenin B
Catalog No.:BCN9263
CAS No.:1161681-20-4
- (+)-Dalbergiphenol
Catalog No.:BCN9262
CAS No.:82358-44-9
- 9-Oxooctadeca-10,12-dienoic acid
Catalog No.:BCN9261
CAS No.:54232-58-5
- Gancaonin O
Catalog No.:BCN9260
CAS No.:129145-53-5
- Jasminoside
Catalog No.:BCN9259
CAS No.:82451-18-1
- threo-Guaiacylglycerol β-coniferyl ether
Catalog No.:BCN9258
CAS No.:168393-18-8
- Matairesinol monoglucoside
Catalog No.:BCN9257
CAS No.:34446-06-5
- 5-O-Methyllatifolin
Catalog No.:BCN9256
CAS No.:18525-14-9
- Cinchonain Ib
Catalog No.:BCN9255
CAS No.:85022-69-1
- 16,23-Oxidoalisol B
Catalog No.:BCN9254
CAS No.:169326-06-1
- Tatsinine
Catalog No.:BCN9267
CAS No.:90038-21-4
- Platyphyllonol 5-O-β-D-xylopyranoside
Catalog No.:BCN9268
CAS No.:288141-04-8
- Cavaol E
Catalog No.:BCN9269
CAS No.:1233044-20-6
- Hedyotol D
Catalog No.:BCN9270
CAS No.:97465-80-0
- Pregn-5-ene-3β,17α,20S-triol
Catalog No.:BCN9271
CAS No.:903-67-3
- 6-Methoxyspirotryprostatin B
Catalog No.:BCN9272
CAS No.:1031727-28-2
- 3-(3-Hydroxybutyl)phenol
Catalog No.:BCN9273
CAS No.:854464-95-2
- Phoyunbene B
Catalog No.:BCN9274
CAS No.:886747-62-2
- Effususol A
Catalog No.:BCN9275
CAS No.:1869082-58-5
- Machigline
Catalog No.:BCN9276
CAS No.:87264-30-0
- Cinnamolide
Catalog No.:BCN9277
CAS No.:23599-47-5
- Cassamedine
Catalog No.:BCN9278
CAS No.:16408-75-6
Active components with inhibitory activities on IFN-gamma/STAT1 and IL-6/STAT3 signaling pathways from Caulis Trachelospermi.[Pubmed:25100250]
Molecules. 2014 Aug 5;19(8):11560-71.
Initial investigation for new active herbal extract with inhibiting activity on JAK/STAT signaling pathway revealed that the extract of Caulis Trachelospermi, which was separated by 80% alcohol extraction and subsequent HP-20 macroporous resin column chromatography, was founded to strongly inhibit IFN-gamma-induced STAT1-responsive luciferase activity (IFN-gamma/STAT1) with IC50 value of 2.43 mug/mL as well as inhibiting IL-6-induced STAT3-responsive luciferase activity (IL-6/STAT3) with IC50 value of 1.38 mug/mL. Subsequent study on its active components led to the isolation and identification of two new dibenzylbutyrolactone lignans named 4-Demethyltraxillaside (1) and nortrachelogenin 4-O-beta-D-glucopyranoside (2), together with six known compounds. The lignan compounds 1-4 together with other lignan compounds isolated in previous study were tested the activities on IFN-gamma/STAT1 and IL-6/STAT3 pathways. The following result showed that the main components trachelogenin and arctigenin had corresponding activities on IFN-gamma/STAT1 pathway with IC50 values of 3.14 muM and 9.46 muM as well as trachelogenin, arctigenin and matairesinol strongly inhibiting IL-6/STAT3 pathway with IC50 values of 3.63 muM, 6.47 muM and 2.92 muM, respectively.
