Anthriscusin

CAS# 67008-16-6

Anthriscusin

Catalog No. BCN3533----Order now to get a substantial discount!

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Quality Control of Anthriscusin

Number of papers citing our products

Chemical structure

Anthriscusin

3D structure

Chemical Properties of Anthriscusin

Cas No. 67008-16-6 SDF Download SDF
PubChem ID 6443833 Appearance Powder
Formula C21H24O7 M.Wt 388.4
Type of Compound Phenylpropanoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(E)-3-(7-methoxy-1,3-benzodioxol-5-yl)prop-2-enyl] (Z)-2-[[(Z)-2-methylbut-2-enoyl]oxymethyl]but-2-enoate
SMILES CC=C(C)C(=O)OCC(=CC)C(=O)OCC=CC1=CC2=C(C(=C1)OC)OCO2
Standard InChIKey FHPUFLKSIYHWOR-SBRHMQLSSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Anthriscusin

The roots of Anthriscus sylvestris

Biological Activity of Anthriscusin

DescriptionStandard reference
In vitro

Antiproliferative constituents in umbelliferae plants. III. Constituents in the root and the ground part of Anthriscus sylvestris Hoffm.[Pubmed: 9621422]

Chem Pharm Bull (Tokyo). 1998 May;46(5):871-4.


METHODS AND RESULTS:
The MeOH extract of the root and the ground part of Anthriscus sylvestris Hoffm. showed a high inhibitory activity against MK-1, HeLa, and B16F10 cell growth in vitro. The activity was found only in the CHCI3-soluble fractions. From the CHCI3-soluble fraction of the root, falcarindiol, 1-(3'-methoxy-4',5'-methylenedioxyphenyl)-1 xi-methoxy-2-propene, elemicin, and nemerosin were newly isolated in addition to deoxypodophyllotoxin (anthricin), Anthriscusin, (-)-deoxypodorhizone, and anthriscinol methyl ether which were reported earlier as constituents of the root of this plant.
CONCLUSIONS:
From the CHCI3-soluble fraction of the ground part, deoxypodophyllotoxin, (-)-deoxypodorhizone, nemerosin, and falcarindiol were isolated. In vitro antiproliferative activities of the isolates against MK-1, HeLa, and B16F10 cells are reported.

Protocol of Anthriscusin

Structure Identification
Chemical & Pharmaceutical Bulletin, 2008 , 26 (4) :1337-1338.

Structure of Anthriscusin, a New Phenylpropanoid Ester from the Roots of Anthriscus sylvestris HOFFM.[Reference: WebLink]


METHODS AND RESULTS:
A new phenylpropanoid ester, Anthriscusin was isolated from the roots of Anthriscus sylvestris HOFFM. (Umbelliferae), and was elucidated as O-[(Z)-2-angeloyloxymethyl-2-butenoyl]-3-methoxy-4,5-methylenedioxycinnamyl alcohol on the basis of the spectral data and the chemical evidence.

Anthriscusin Dilution Calculator

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Anthriscusin Molarity Calculator

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Preparing Stock Solutions of Anthriscusin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5747 mL 12.8733 mL 25.7467 mL 51.4933 mL 64.3666 mL
5 mM 0.5149 mL 2.5747 mL 5.1493 mL 10.2987 mL 12.8733 mL
10 mM 0.2575 mL 1.2873 mL 2.5747 mL 5.1493 mL 6.4367 mL
50 mM 0.0515 mL 0.2575 mL 0.5149 mL 1.0299 mL 1.2873 mL
100 mM 0.0257 mL 0.1287 mL 0.2575 mL 0.5149 mL 0.6437 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Anthriscusin

Antiproliferative constituents in umbelliferae plants. III. Constituents in the root and the ground part of Anthriscus sylvestris Hoffm.[Pubmed:9621422]

Chem Pharm Bull (Tokyo). 1998 May;46(5):871-4.

The MeOH extract of the root and the ground part of Anthriscus sylvestris Hoffm. showed a high inhibitory activity against MK-1, HeLa, and B16F10 cell growth in vitro. The activity was found only in the CHCI3-soluble fractions. From the CHCI3-soluble fraction of the root, falcarindiol, 1-(3'-methoxy-4',5'-methylenedioxyphenyl)-1 xi-methoxy-2-propene, elemicin, and nemerosin were newly isolated in addition to deoxypodophyllotoxin (anthricin), Anthriscusin, (-)-deoxypodorhizone, and anthriscinol methyl ether which were reported earlier as constituents of the root of this plant. From the CHCI3-soluble fraction of the ground part, deoxypodophyllotoxin, (-)-deoxypodorhizone, nemerosin, and falcarindiol were isolated. In vitro antiproliferative activities of the isolates against MK-1, HeLa, and B16F10 cells are reported.

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