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Bisphenol P

CAS# 2167-51-3

Bisphenol P

2D Structure

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Bisphenol P: 5mg $17 In Stock
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3D structure

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Bisphenol P

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Chemical Properties of Bisphenol P

Cas No. 2167-51-3 SDF Download SDF
PubChem ID 630355 Appearance Powder
Formula C24H26O2 M.Wt 346.5
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4-[2-[4-[2-(4-hydroxyphenyl)propan-2-yl]phenyl]propan-2-yl]phenol
SMILES CC(C)(C1=CC=C(C=C1)C(C)(C)C2=CC=C(C=C2)O)C3=CC=C(C=C3)O
Standard InChIKey GIXXQTYGFOHYPT-UHFFFAOYSA-N
Standard InChI InChI=1S/C24H26O2/c1-23(2,19-9-13-21(25)14-10-19)17-5-7-18(8-6-17)24(3,4)20-11-15-22(26)16-12-20/h5-16,25-26H,1-4H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Bisphenol P Dilution Calculator

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Bisphenol P Molarity Calculator

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Preparing Stock Solutions of Bisphenol P

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.886 mL 14.43 mL 28.86 mL 57.7201 mL 72.1501 mL
5 mM 0.5772 mL 2.886 mL 5.772 mL 11.544 mL 14.43 mL
10 mM 0.2886 mL 1.443 mL 2.886 mL 5.772 mL 7.215 mL
50 mM 0.0577 mL 0.2886 mL 0.5772 mL 1.1544 mL 1.443 mL
100 mM 0.0289 mL 0.1443 mL 0.2886 mL 0.5772 mL 0.7215 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Bisphenol P

Bisphenol P activates hormonal genes and introduces developmental outcomes in Chironomus tentans.[Pubmed:30878007]

Ecotoxicol Environ Saf. 2019 Jun 15;174:675-682.

The endocrine disrupting properties of bisphenol A (BPA) discharged to the environment have been newly identified by the European Chemicals Agency, increasing the need to assess the environmental endocrine disrupting potentials of its alternatives with which it shares close structural features. However, few investigations of the environmental endocrine disrupting functions of BPA analogs have been conducted to date. In this study, the endocrine disrupting effects of a BPA analog of Bisphenol P (BPP) were investigated in the nonbiting midge (Chironomus tentans), a model organism in ecotoxicology. An initial ex vivo test using salivary gland cells explanted from the larvae and a subsequent in vivo test using embryos and larvae revealed the upregulatory effects of BPP on ecdysone receptor genes encoding the ecdysone receptor (EcR) and the early responsive gene E74, with a similar temporal pattern of gene activation. Partial life cycle and full life cycle toxicity tests demonstrated BPP altered embryo hatching, larval emergence, and adult sex ratio at concentrations close to the effective concentrations for hormonal genetic endpoints in embryos and larvae after 48h of exposure. Although embryos appeared to be more sensitive to BPP than the fourth instar larvae, the impact on neither life stage seemed enough to estimate the developmental impairment of the insects. These results demonstrate the ecdysone pathway is a target of BPP, and that long-term exposure could cause apical effects on the development of C. tentans. The endocrine disrupting effects towards aquatic organisms, as well as the high persistence and bioconcentration potential, indicate an urgent need to assess the environmental risks associated with BPP.

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