CarpesiolinCAS# 63568-73-0 |
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| Cas No. | 63568-73-0 | SDF | Download SDF |
| PubChem ID | 325797.0 | Appearance | Powder |
| Formula | C15H20O4 | M.Wt | 264.13 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 9-hydroxy-5,8a-dimethyl-1-methylidene-3a,4,5,5a,6,7,9,9a-octahydroazuleno[6,7-b]furan-2,8-dione | ||
| SMILES | CC1CC2C(C(C3(C1CCC3=O)C)O)C(=C)C(=O)O2 | ||
| Standard InChIKey | IOUNDPHKKPZPKB-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C15H20O4/c1-7-6-10-12(8(2)14(18)19-10)13(17)15(3)9(7)4-5-11(15)16/h7,9-10,12-13,17H,2,4-6H2,1,3H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Carpesiolin Dilution Calculator
Carpesiolin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.786 mL | 18.9301 mL | 37.8601 mL | 75.7203 mL | 94.6504 mL |
| 5 mM | 0.7572 mL | 3.786 mL | 7.572 mL | 15.1441 mL | 18.9301 mL |
| 10 mM | 0.3786 mL | 1.893 mL | 3.786 mL | 7.572 mL | 9.465 mL |
| 50 mM | 0.0757 mL | 0.3786 mL | 0.7572 mL | 1.5144 mL | 1.893 mL |
| 100 mM | 0.0379 mL | 0.1893 mL | 0.3786 mL | 0.7572 mL | 0.9465 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Cytotoxic sesquiterpene lactones from Carpesium abrotanoides.[Pubmed:12221601]
Planta Med. 2002 Aug;68(8):745-7.
Eight sesquiterpene lactones, 4 alpha,5 alpha-epoxy-10 alpha,14-dihydro-inuviscolide (1), 2,3-dihydroaromomaticin (2), Carpesiolin (3), carabrone (4), carabrol (5), telekin (6), ivalin (7) and 11,13-didehydroivaxillin (8), were isolated from the aerial parts of Carpesium abrotanoides Linne (Compositae). In vitro cytotoxicity testing was carried out against L1210, A549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15 tumor cell lines. Sesquiterpene lactone compounds 1 - 8 showed significant cytotoxic activity (ED50 values, < 20 microM) against all tumor call lines tested. Among these compounds, 4 alpha,5 alpha-epoxy-10 alpha,14-dihydro-inuviscolide (1), 2,3-dihydroaromomaticin (2), telekin (6) and ivalin (7) showed cytotoxic activity (ED50, < 10 microM) comparable to that of cisplatin.
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