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Ganolucidic acid B

CAS# 98683-75-1

Ganolucidic acid B

2D Structure

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Ganolucidic acid B

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Chemical Properties of Ganolucidic acid B

Cas No. 98683-75-1 SDF Download SDF
PubChem ID 20055994 Appearance Powder
Formula C30H46O6 M.Wt 502.7
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (6R)-6-[(3S,5R,10S,13R,14R,15S,17R)-3,15-dihydroxy-4,4,10,13,14-pentamethyl-11-oxo-1,2,3,5,6,7,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid
SMILES CC(CC(=O)CC(C)C(=O)O)C1CC(C2(C1(CC(=O)C3=C2CCC4C3(CCC(C4(C)C)O)C)C)C)O
Standard InChIKey YPYHGMCHNBTMDB-GOGDEKJESA-N
Standard InChI InChI=1S/C30H46O6/c1-16(12-18(31)13-17(2)26(35)36)20-14-24(34)30(7)19-8-9-22-27(3,4)23(33)10-11-28(22,5)25(19)21(32)15-29(20,30)6/h16-17,20,22-24,33-34H,8-15H2,1-7H3,(H,35,36)/t16-,17?,20-,22+,23+,24+,28+,29-,30-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Ganolucidic acid B

The fruit body of Ganoderma lucidum

Ganolucidic acid B Dilution Calculator

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Ganolucidic acid B Molarity Calculator

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Preparing Stock Solutions of Ganolucidic acid B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9893 mL 9.9463 mL 19.8926 mL 39.7852 mL 49.7315 mL
5 mM 0.3979 mL 1.9893 mL 3.9785 mL 7.957 mL 9.9463 mL
10 mM 0.1989 mL 0.9946 mL 1.9893 mL 3.9785 mL 4.9731 mL
50 mM 0.0398 mL 0.1989 mL 0.3979 mL 0.7957 mL 0.9946 mL
100 mM 0.0199 mL 0.0995 mL 0.1989 mL 0.3979 mL 0.4973 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ganolucidic acid B

Deciphering the chemical composition of Ganoderma lucidum from different geographical origins by mass spectrometry molecular networking coupled with multivariate analysis.[Pubmed:36093881]

Biomed Chromatogr. 2022 Sep 12:e5506.

Ganoderma lucidum is a medicinal fungus that has been widely used in China and many Asian countries for thousands of years. This once rare macrofungus has now been artificially cultivated in a number of regions in China. However, detailed knowledge of its composition across different geographical origins is still lacking, as are analytical methods for comprehensive profiling of the diverse phytochemicals contained in G. lucidum. In this work, an on-demand strategy based on high-resolution MS and molecular networking is applied for natural product characterization, which led to the identification of 84 constituents in G. lucidum. Moreover, multivariate analysis, including hierarchical cluster analysis and orthogonal partial least squares-discriminant analysis, was used to analyze the (dis)similarity of the G. lucidum samples collected from the three main production areas (i.e., Jilin, Henan and Shandong Province). The results revealed a significant variation in the chemical composition of samples from different provinces. Marker constituents corresponding to the differentiation were then screened in terms of the variable importance in projection value, P-value and fold change. A total of 24 constituents were identified as geoherbalism markers, such as ganoderenic acid A for Henan, Ganolucidic acid B for Jilin and ganodernoid D for Shandong. This proof-of-concept application demonstrates that combining MS molecular networking with meticulous multivariate analysis can provide a sensitive and comprehensive analytical approach for the quality assessment of traditional Chinese medicine ingredients. This study also suggests that the bioactivity and efficacy from different origins should be further evaluated considering the large difference in chemical compositions.

[Triterpenoids from Ganoderma theaecolum].[Pubmed:28875673]

Zhongguo Zhong Yao Za Zhi. 2016 Mar;41(6):1075-1080.

Fifteenlanostane triterpenoids were isolated from the ethanol extract of Ganoderma theaecolum by means of preparative HPLC,column chromatography over silica gel,ODS and were identified as lucidone C(1),lucidone D(2),7-oxo-ganoderic acid Z2(3),7-oxo-ganoderic acid Z(4),ganoderenicacid H(5),ganoderenic acid B(6),3beta,7beta-dihydroyl-11,15,23-trioxo-lanost-8,16-dien-26-oic acid(7),3beta,7beta-dihydroyl-11,15,23-trioxo-lanost-8,16-dien-26-oic acid methyl ester(8),Ganolucidic acid B(9),ganolucidate F(10),methyl ganoderate C2(11),ganoderic acid zeta(12),ganoderic acid AP3(13),methyl ganoderate B(14),and ganoderol B(15). Compounds 1-15 were isolated from this specie for the first time.

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