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Ganolucidic acid A

CAS# 98665-21-5

Ganolucidic acid A

Catalog No. BCN2444----Order now to get a substantial discount!

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Quality Control of Ganolucidic acid A

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Chemical structure

Ganolucidic acid A

3D structure

Chemical Properties of Ganolucidic acid A

Cas No. 98665-21-5 SDF Download SDF
PubChem ID 475412 Appearance Powder
Formula C30H44O6 M.Wt 500.67
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R,6R)-6-[(5R,10S,13R,14R,15S,17R)-15-hydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid
SMILES CC(CC(=O)CC(C)C(=O)O)C1CC(C2(C1(CC(=O)C3=C2CCC4C3(CCC(=O)C4(C)C)C)C)C)O
Standard InChIKey XRXBNTYHQXKSAO-WRRQQOFWSA-N
Standard InChI InChI=1S/C30H44O6/c1-16(12-18(31)13-17(2)26(35)36)20-14-24(34)30(7)19-8-9-22-27(3,4)23(33)10-11-28(22,5)25(19)21(32)15-29(20,30)6/h16-17,20,22,24,34H,8-15H2,1-7H3,(H,35,36)/t16-,17-,20-,22+,24+,28+,29-,30-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Ganolucidic acid A

The fruit body of Ganoderma lucidum

Biological Activity of Ganolucidic acid A

Description1. Ganolucidic acid A exhibits cytotoxicity, has inhibitory activities against human HeLa cervical cancer cell lines. 2. Ganolucidic acid A shows significant anti-human immunodeficiency virus (anti-HIV)-1 protease activity with IC50 values of 20-90 microM.

Ganolucidic acid A Dilution Calculator

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Ganolucidic acid A Molarity Calculator

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Preparing Stock Solutions of Ganolucidic acid A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9973 mL 9.9866 mL 19.9732 mL 39.9465 mL 49.9331 mL
5 mM 0.3995 mL 1.9973 mL 3.9946 mL 7.9893 mL 9.9866 mL
10 mM 0.1997 mL 0.9987 mL 1.9973 mL 3.9946 mL 4.9933 mL
50 mM 0.0399 mL 0.1997 mL 0.3995 mL 0.7989 mL 0.9987 mL
100 mM 0.02 mL 0.0999 mL 0.1997 mL 0.3995 mL 0.4993 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ganolucidic acid A

Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease.[Pubmed:9810695]

Chem Pharm Bull (Tokyo). 1998 Oct;46(10):1607-12.

Two new lanostane-type triterpenes, lucidumol A and ganoderic acid beta, were isolated from the spores of Ganoderma (G.) lucidum, together with a new natural one and seven that were known. The structures of the new triterpenes were determined as (24S)-24,25-dihydroxylanost-8-ene-3,7-dione and 3 beta,7 beta-dihydroxy-11,15-dioxolanosta-8,24(E)-dien-26-oic acid, respectively, by chemical and spectroscopic means. The quantitative analyses of 5 fruiting bodies, antlered form and spores of G. lucidum were performed by high performance liquid chromatography and demonstrated that ganoderic alcohol and acid contents were quite high in the spore. Of the compound isolated, ganoderic acid beta, (24S)-lanosta-7,9(11)-diene-3 beta,24,25-triol (called lucidumol B), ganodermanondiol, ganodermanontriol and Ganolucidic acid A showed significant anti-human immunodeficiency virus (anti-HIV)-1 protease activity with IC50 values of 20-90 microM.

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