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ATP disodium salt

P2 purinergic agonist CAS# 987-65-5

ATP disodium salt

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Chemical structure

ATP disodium salt

3D structure

Chemical Properties of ATP disodium salt

Cas No. 987-65-5 SDF Download SDF
PubChem ID 13803 Appearance Powder
Formula C10H14N5Na2O13P3 M.Wt 551.14
Type of Compound N/A Storage Desiccate at -20°C
Synonyms Adetide; Triadesin A; Triphosadenine;
Solubility H2O : 100 mg/mL (181.44 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Chemical Name disodium;[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] hydrogen phosphate
SMILES [Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO[P](O)(=O)O[P]([O-])(=O)O[P](O)([O-])=O)[C@@H](O)[C@H]3O
Standard InChIKey TTWYZDPBDWHJOR-IDIVVRGQSA-L
Standard InChI InChI=1S/C10H16N5O13P3.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of ATP disodium salt

DescriptionP2 purinoceptor agonist.

ATP disodium salt Dilution Calculator

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ATP disodium salt Molarity Calculator

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Preparing Stock Solutions of ATP disodium salt

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.8144 mL 9.0721 mL 18.1442 mL 36.2884 mL 45.3605 mL
5 mM 0.3629 mL 1.8144 mL 3.6288 mL 7.2577 mL 9.0721 mL
10 mM 0.1814 mL 0.9072 mL 1.8144 mL 3.6288 mL 4.5361 mL
50 mM 0.0363 mL 0.1814 mL 0.3629 mL 0.7258 mL 0.9072 mL
100 mM 0.0181 mL 0.0907 mL 0.1814 mL 0.3629 mL 0.4536 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Background on ATP disodium salt

ATP Disodium salt is a P2 purinoceptor agonist.

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References on ATP disodium salt

Fluorescence and chemiluminescence behavior of distyrylbenzene bearing two arms of dipicolylaminomethyl groups: Interactions with zinc ion and ATP.[Pubmed:29414582]

Spectrochim Acta A Mol Biomol Spectrosc. 2018 Apr 15;195:223-229.

The absorption and fluorescence spectral study of the distyrylbenzene bearing two arms of the dipicolylaminomethyl groups, the effective ligands for Zn(2+), was studied in the presence of Zn(2+) and ATP. Upon complexation of the distyrylbenzene with zinc ions in acetonitrile, enhancement of the fluorescence intensity was observed due to inhibition of intramolecular PET (photo-induced electron transfer) quenching, but no effect was found in aqueous media because the equilibrium laid to the free form of the ligands. In contrast, the addition of ATP disodium salt was effective to enhance the fluorescence intensity of the combination of the distyrylbenzne and Zn(2+) in aqueous media. This assembly was applied to the peroxyoxalate chemiluminescence system and a significant increase in the intensity was observed, which provides a potential detection for ATP by chemiluminescence.

Description

ATP disodium salt is a phosphate-group donor for substrate activation in metabolic reactions and the coenzyme for a large number of kinases.

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