Inonotusol FCAS# 1534433-74-3 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
| Cas No. | 1534433-74-3 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C31H48O3 | M.Wt | 468.71 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Inonotusol F Dilution Calculator
Inonotusol F Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.1335 mL | 10.6676 mL | 21.3352 mL | 42.6703 mL | 53.3379 mL |
| 5 mM | 0.4267 mL | 2.1335 mL | 4.267 mL | 8.5341 mL | 10.6676 mL |
| 10 mM | 0.2134 mL | 1.0668 mL | 2.1335 mL | 4.267 mL | 5.3338 mL |
| 50 mM | 0.0427 mL | 0.2134 mL | 0.4267 mL | 0.8534 mL | 1.0668 mL |
| 100 mM | 0.0213 mL | 0.1067 mL | 0.2134 mL | 0.4267 mL | 0.5334 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Inhibitory effect of triterpenoids from the mushroom Inonotus obliquus against alpha-glucosidase and their interaction: Inhibition kinetics and molecular stimulations.[Pubmed:34426146]
Bioorg Chem. 2021 Oct;115:105276.
Bioassay-guided fractionation led to the isolation of a series of triterpenoids (1-46) including 12 new ones (1-12) from the mushroom Inonotus obliquus. The structures of all the compounds were elucidated by spectroscopic analysis as well as by comparison with literature data. Triterpenoids 1-3, 6, 7, 16, 24, 25, 27, 38, 43, 44 and 46 showed strong alpha-glucosidase inhibition, with IC(50) values from 11.5 to 81.8 muM. Their structure-activity relationships were discussed. Inonotusol F (24) showed the strongest inhibitory activity and it presented noncompetitive inhibition against alpha-glucosidase. Molecular docking and molecular dynamics stimulation further demonstrated that GLU302 and PHE298 were key amino acids for the inhibition of Inonotusol F (24) towards alpha-glucosidase. This study indicates the vital role of triterpenoids in explaining hypoglycemic effect of Inonotus obliquus and provides important evidence for further development and utilization of this mushroom.
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