LipodeoxyaconitineCAS# 244190-83-8 |
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| Cas No. | 244190-83-8 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Oil |
| Formula | C50H75NO10 | M.Wt | 850.1 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Lipodeoxyaconitine Dilution Calculator
Lipodeoxyaconitine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.1763 mL | 5.8817 mL | 11.7633 mL | 23.5266 mL | 29.4083 mL |
| 5 mM | 0.2353 mL | 1.1763 mL | 2.3527 mL | 4.7053 mL | 5.8817 mL |
| 10 mM | 0.1176 mL | 0.5882 mL | 1.1763 mL | 2.3527 mL | 2.9408 mL |
| 50 mM | 0.0235 mL | 0.1176 mL | 0.2353 mL | 0.4705 mL | 0.5882 mL |
| 100 mM | 0.0118 mL | 0.0588 mL | 0.1176 mL | 0.2353 mL | 0.2941 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Hypaconitine, the dominant constituent responsible for the neuromuscular blocking action of the Japanese-sino medicine "bushi" (aconite root).[Pubmed:3210453]
Jpn J Pharmacol. 1988 Oct;48(2):290-3.
The neuromuscular blocking actions of several constituents extracted from Japanese-sino medicine, aconite, were compared in mouse phrenic nerve-diaphragm muscle preparations. Hypaconitine (HAT) was more potent than aconitine (ATN), mesaconitine (MAT) and deoxyaconitine. Lipohypaconitine, coryneine and Lipodeoxyaconitine were less effective. Lipoaconitine, benzoylmesaconine, higenamine, kobusine and chasmanine were not effective. The blockades by HAT, ATN and MAT were not recovered by neostigmine. The mechanisms of blockade were similar to that of aconite crude extract. These results suggest that aconite action is dependent on HAT, a main constituent.
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