Peanut procyanidin FCAS# 2095621-25-1 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
| Cas No. | 2095621-25-1 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C60H46O24 | M.Wt | 1151 |
| Type of Compound | Procyanidins | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Peanut procyanidin F Dilution Calculator
Peanut procyanidin F Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 0.8688 mL | 4.344 mL | 8.6881 mL | 17.3762 mL | 21.7202 mL |
| 5 mM | 0.1738 mL | 0.8688 mL | 1.7376 mL | 3.4752 mL | 4.344 mL |
| 10 mM | 0.0869 mL | 0.4344 mL | 0.8688 mL | 1.7376 mL | 2.172 mL |
| 50 mM | 0.0174 mL | 0.0869 mL | 0.1738 mL | 0.3475 mL | 0.4344 mL |
| 100 mM | 0.0087 mL | 0.0434 mL | 0.0869 mL | 0.1738 mL | 0.2172 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Trimeric and Tetrameric A-Type Procyanidins from Peanut Skins.[Pubmed:28231711]
J Nat Prod. 2017 Feb 24;80(2):415-426.
Peanut skins are a rich source of oligomeric and polymeric procyanidins. The oligomeric fractions are dominated by dimers, trimers, and tetramers. A multistep chromatographic fractionation led to the isolation of four new A-type procyanidins of tri- and tetrameric structures. The structures of the new trimers were defined by NMR, electronic circular dichroism, and MS data as epicatechin-(4beta-->8,2beta-->O-->7)-epicatechin-(4beta-->8,2beta-->O-->7)-catec hin, peanut procyanidin B (3), and epicatechin-(4beta-->8,2beta-->O-->7)-epicatechin-(4beta-->6)-catechin, peanut procyanidin C (4). The new tetramers were defined as epicatechin-(4beta-->8,2beta-->O-->7)-epicatechin-(4beta-->6)-epicatechin-(4beta- ->8,2beta-->O-->7)-catechin, peanut procyanidin E (1), and epicatechin-(4beta-->8,2beta-->O-->7)-epicatechin-(4beta-->6)-epicatechin-(4beta- ->8,2beta-->O-->7)-epicatechin, Peanut procyanidin F (2). In addition, both A-type dimers A1, epicatechin-(4beta-->8,2beta-->O-->7)-catechin, and A2, epicatechin-(4beta-->8,2beta-->O-->7)-epicatechin, as well as two known peanut trimers, ent-epicatechin-(4beta-->6)-epicatechin-(4beta-->8,2beta-->O-->7)-catechin, peanut procyanidin A (5), and epicatechin-(4beta-->8)-epicatechin-(4beta-->8,2beta-->O-->7)-catechin, peanut procyanidin D (6), were also isolated. Dimer A1, the four trimers, and two tetramers were evaluated for anti-inflammatory activity in an in vitro assay, in which LPS-stimulated macrophages were responding with secretion of TNF-alpha, a pro-inflammatory cytokine. Tetramer F (2) was the most potent, suppressing TNF-alpha secretion to 82% at 8.7 muM (10 mug/mL), while tetramer E (1) at the same concentrations caused a 4% suppression. The results of the TNF-alpha secretion inhibition indicate that small structural differences, as in peanut procyanidin tetramers E and F, can be strongly differentiated in biological systems.
