Rebaudioside NCAS# 1220616-46-5 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
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Cas No. | 1220616-46-5 | SDF | Download SDF |
PubChem ID | 138115160 | Appearance | White powder |
Formula | C56H90O32 | M.Wt | 1275.3 |
Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
Solubility | Soluble in methan | ||
Chemical Name | [5-hydroxy-6-(hydroxymethyl)-4-[(2S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl] (1R,4R,5R,9S,10R,13S)-13-[(2S)-5-hydroxy-6-(hydroxymethyl)-3,4-bis[[(2S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]oxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylate | ||
SMILES | CC1C(C(C(C(O1)OC2C(C(C(OC2OC(=O)C3(CCCC4(C3CCC56C4CCC(C5)(C(=C)C6)OC7C(C(C(C(O7)CO)O)OC8C(C(C(C(O8)CO)O)O)O)OC9C(C(C(C(O9)CO)O)O)O)C)C)CO)O)OC1C(C(C(C(O1)CO)O)O)O)O)O)O | ||
Standard InChIKey | AKEKAGBWNXIWSS-SWXNTNRLSA-N | ||
Standard InChI | InChI=1S/C56H90O32/c1-19-12-55-10-6-26-53(3,8-5-9-54(26,4)52(76)87-50-44(85-46-38(72)34(68)28(62)20(2)77-46)42(32(66)24(16-60)81-50)83-47-39(73)35(69)29(63)21(13-57)78-47)27(55)7-11-56(19,18-55)88-51-45(86-49-41(75)37(71)31(65)23(15-59)80-49)43(33(67)25(17-61)82-51)84-48-40(74)36(70)30(64)22(14-58)79-48/h20-51,57-75H,1,5-18H2,2-4H3/t20?,21?,22?,23?,24?,25?,26-,27+,28?,29?,30?,31?,32?,33?,34?,35?,36?,37?,38?,39?,40?,41?,42?,43?,44?,45?,46+,47+,48+,49+,50?,51+,53-,54-,55-,56+/m1/s1 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
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Rebaudioside N Dilution Calculator
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Rebaudioside N Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 0.7841 mL | 3.9206 mL | 7.8413 mL | 15.6826 mL | 19.6032 mL |
5 mM | 0.1568 mL | 0.7841 mL | 1.5683 mL | 3.1365 mL | 3.9206 mL |
10 mM | 0.0784 mL | 0.3921 mL | 0.7841 mL | 1.5683 mL | 1.9603 mL |
50 mM | 0.0157 mL | 0.0784 mL | 0.1568 mL | 0.3137 mL | 0.3921 mL |
100 mM | 0.0078 mL | 0.0392 mL | 0.0784 mL | 0.1568 mL | 0.196 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
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Coupling biological detection to liquid chromatography: a new tool in drug discovery.[Pubmed:29063136]
Naunyn Schmiedebergs Arch Pharmacol. 2018 Jan;391(1):9-16.
Procedures to characterize drugs that can be obtained from plant extracts or combinatorial chemistry are tedious, and they consume considerable resources (e.g., animals) and time. Thus, we have looked for a way to streamline this process. We describe here a novel system for the pre-characterization of drugs based on liquid chromatography coupled to biological detection using perifused or perfused organs. This novel system allows the on-line detection of pharmacologically active substances in hydrosoluble mixtures from vegetal extracts or combinatorial chemistry libraries. Depending on the volume of drug solution and concentration of the samples, the procedure can work through either medium pressure liquid chromatography or HPLC, and it enables the fingerprints of drugs to be assessed based on their contractile activity on combinations of different isolated tissues. As an example, we show how the system can identify active fractions from an extract of Stevia rebaudiana Bertoni, an activity that was later associated with Rebaudioside N. Coupling liquid chromatography to biological detection offers a rapid way to focus attention on active products in complex samples, mostly from hydrosoluble species, helping to considerably reduce the time and cost of the pre-characterization of drugs.