Home >> Research Area >>Natural Products>>Xanthones>> Epigambogic acid

Epigambogic acid

CAS# 887606-04-4

Epigambogic acid

Catalog No. BCN9109----Order now to get a substantial discount!

Product Name & Size Price Stock
Epigambogic acid: 5mg $236 In Stock
Epigambogic acid: 10mg Please Inquire In Stock
Epigambogic acid: 20mg Please Inquire Please Inquire
Epigambogic acid: 50mg Please Inquire Please Inquire
Epigambogic acid: 100mg Please Inquire Please Inquire
Epigambogic acid: 200mg Please Inquire Please Inquire
Epigambogic acid: 500mg Please Inquire Please Inquire
Epigambogic acid: 1000mg Please Inquire Please Inquire

Quality Control of Epigambogic acid

Number of papers citing our products

Chemical structure

Epigambogic acid

Chemical Properties of Epigambogic acid

Cas No. 887606-04-4 SDF Download SDF
PubChem ID N/A Appearance Powder
Formula C38H44O8 M.Wt 628.75
Type of Compound Xanthones Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Epigambogic acid Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Epigambogic acid Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Epigambogic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.5905 mL 7.9523 mL 15.9046 mL 31.8091 mL 39.7614 mL
5 mM 0.3181 mL 1.5905 mL 3.1809 mL 6.3618 mL 7.9523 mL
10 mM 0.159 mL 0.7952 mL 1.5905 mL 3.1809 mL 3.9761 mL
50 mM 0.0318 mL 0.159 mL 0.3181 mL 0.6362 mL 0.7952 mL
100 mM 0.0159 mL 0.0795 mL 0.159 mL 0.3181 mL 0.3976 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Epigambogic acid

Rapid determination of polyprenylated xanthones in gamboge resin of Garcinia hanburyi by HPLC.[Pubmed:17396587]

J Sep Sci. 2007 Feb;30(3):304-9.

A rapid ion-pair HPLC method was developed and validated for the determination of eight polyprenylated xanthones including three pairs of epimers, namely morellic acid (MA), 30-hydroxygambogic acid (HGA), 30-hydroxyEpigambogic acid (HEGA), isogambogic acid (IGA), epiisogambogic acid (EIGA), gambogenic acid (GNA), gambogic acid (GA), and Epigambogic acid (EGA), in gamboge resin of Garcinia hanburyi. The separation was performed on a narrow bore C8 column with isocratic elution using a mixture of methanol-ACN-40 mM KH2PO4 buffer (37.5:37.5:25 v/v/v, containing 0.1% tetradecyltrimethylammonium bromide). The newly developed method was used to determine the contents of the eight compounds present in the gamboge. Results showed that GA and EGA are the dominant components of gamboge. The content ratio of each epimer pair remained constant, indicating that the content ratio of epimers can be used as a specific characteristic for the quality control of gamboge.

Preparative separation of gambogic acid and its C-2 epimer using recycling high-speed counter-current chromatography.[Pubmed:16887130]

J Chromatogr A. 2006 Sep 15;1127(1-2):298-301.

A recycling counter-current chromatographic system was first set up with a high-speed counter-current chromatography instrument coupled with a column switching valve. This system was first successfully applied to the preparative separation of epimers, gambogic acid and Epigambogic acid from Garcinia hanburyi using n-hexane-methanol-water (5:4:1, v/v/v) as the two-phase solvent system. As a result, 28.2 mg gambogic acid and 18.4 mg Epigambogic acid were separated from 50 mg of mixture. Their purities were both above 97% as determined by HPLC. The chemical structures were then identified by their (1)H NMR and (13)C NMR spectra.

Gambogic acid and epigambogic acid, C-2 epimers with novel anticancer effects from Garcinia hanburyi.[Pubmed:16534739]

Planta Med. 2006 Feb;72(3):281-4.

Gambogic acid, usually isolated as an inseparable stereomeric mixture of C-2 epimers, was newly separated into two epimers (1 and 2) from the gamboges of Garcinia hanburyi. The stereochemistry at C-2 was clearly defined by extensive spectroscopic analysis and direct comparison of NMR and HPLC data with those of the known R-epimer. Both epimers were examined for their cytotoxicities against human leukemia K562 (K562/S) and doxorubicin-resistant K562 (K562/R) cell lines. Different from doxorubicin (IC (50) = 10.78 microM for K562/R and 0.66 microM for K562/S), epimers 1 and 2 exhibited similar activities against both cell lines (IC(50) = 1.32 and 0.89 microM for 1, IC(50) = 1.11 and 0.86 microM for 2). These results suggested that both epimers were not multidrug resistance (MDR) substrates. Furthermore, epimers 1 and 2 were tested for their inhibitory effects against six human cytochrome P-450 enzymes. Epimers 1 and 2 showed little inhibitory effects toward five of the enzymes except CYP2C9. Interestingly, when tested against CYP2C9, S-epimer 2 had an inhibitory effect 20-fold stronger than that of R-epimer 1.

Keywords:

Epigambogic acid,887606-04-4,Natural Products, buy Epigambogic acid , Epigambogic acid supplier , purchase Epigambogic acid , Epigambogic acid cost , Epigambogic acid manufacturer , order Epigambogic acid , high purity Epigambogic acid

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: