Home >> Research Area >>Natural Products>> Sibiriquinone A

Sibiriquinone A

CAS# 723300-08-1

Sibiriquinone A

Catalog No. BCX1885----Order now to get a substantial discount!

Product Name & Size Price Stock
Sibiriquinone A: 5mg Please Inquire In Stock
Sibiriquinone A: 10mg Please Inquire In Stock
Sibiriquinone A: 20mg Please Inquire Please Inquire
Sibiriquinone A: 50mg Please Inquire Please Inquire
Sibiriquinone A: 100mg Please Inquire Please Inquire
Sibiriquinone A: 200mg Please Inquire Please Inquire
Sibiriquinone A: 500mg Please Inquire Please Inquire
Sibiriquinone A: 1000mg Please Inquire Please Inquire

Quality Control of Sibiriquinone A

Number of papers citing our products

Chemical structure

Sibiriquinone A

Chemical Properties of Sibiriquinone A

Cas No. 723300-08-1 SDF Download SDF
PubChem ID N/A Appearance Powder
Formula C19H20O2 M.Wt 280.36
Type of Compound N/A Storage Desiccate at -20°C
Synonyms 7,8-Dihydro-8,8-dimethyl-2-(1-methylethyl)-1,4-phenanthrenedione
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Sibiriquinone A Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Sibiriquinone A Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Sibiriquinone A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.5668 mL 17.8342 mL 35.6684 mL 71.3369 mL 89.1711 mL
5 mM 0.7134 mL 3.5668 mL 7.1337 mL 14.2674 mL 17.8342 mL
10 mM 0.3567 mL 1.7834 mL 3.5668 mL 7.1337 mL 8.9171 mL
50 mM 0.0713 mL 0.3567 mL 0.7134 mL 1.4267 mL 1.7834 mL
100 mM 0.0357 mL 0.1783 mL 0.3567 mL 0.7134 mL 0.8917 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Sibiriquinone A

Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1.[Pubmed:17583950]

J Nat Prod. 2007 Jul;70(7):1093-7.

The hypoxia-inducible factor-1 (HIF-1) has been known to be correlated to the adaptation and proliferation of tumor cells; therefore HIF-1 has become an important target in the development of anticancer drugs. A phytochemical study of the CHCl3-soluble fraction of Salvia miltiorrhiza, which strongly inhibited hypoxia-induced reporter gene expression, led to the isolation of 12 abietane-type diterpenes. Of these compounds, Sibiriquinone A (1), sibiriquinone B (2), cryptotanshinone (3), and dihydrotanshinone I (4) potently inhibited hypoxia-induced luciferase expression with IC50 values of 0.34, 3.36, 1.58, and 2.05 microM on AGS cells, a human gastric cancer cell line, and 0.28, 3.18, 1.36, and 2.29 microM on Hep3B cells, a human hepatocarcinoma cell line, respectively. Consistently, 1 and 4 dose-dependently suppressed the HIF-1alpha accumulation and 1 inhibited mRNA expression of vascular endothelial growth factor (VEGF) under hypoxia. These results suggest that the anticancer activity of tanshinones is likely at least in part associated with their inhibition of HIF-1 accumulation.

Immunosuppressive diterpenes from Veronicastrum sibiricum.[Pubmed:14709882]

Chem Pharm Bull (Tokyo). 2004 Jan;52(1):136-7.

Two new diterpenes, named Sibiriquinone A (1) and B (2), along with four known diterpenes have been isolated from the aerial part of Veronicastrum sibiricum. Their structures were elucidated by spectroscopy. The isolated compounds showed significant immunosuppressive activities.

Keywords:

Sibiriquinone A,723300-08-1,7,8-Dihydro-8,8-dimethyl-2-(1-methylethyl)-1,4-phenanthrenedione,Natural Products, buy Sibiriquinone A , Sibiriquinone A supplier , purchase Sibiriquinone A , Sibiriquinone A cost , Sibiriquinone A manufacturer , order Sibiriquinone A , high purity Sibiriquinone A

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: