Yunnancoronarin BCAS# 162762-94-9 |
Quality Control & MSDS
Package In Stock
Number of papers citing our products
| Cas No. | 162762-94-9 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C20H28O3 | M.Wt | 316.48 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Yunnancoronarin B Dilution Calculator
Yunnancoronarin B Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.1598 mL | 15.7988 mL | 31.5976 mL | 63.1951 mL | 78.9939 mL |
| 5 mM | 0.632 mL | 3.1598 mL | 6.3195 mL | 12.639 mL | 15.7988 mL |
| 10 mM | 0.316 mL | 1.5799 mL | 3.1598 mL | 6.3195 mL | 7.8994 mL |
| 50 mM | 0.0632 mL | 0.316 mL | 0.632 mL | 1.2639 mL | 1.5799 mL |
| 100 mM | 0.0316 mL | 0.158 mL | 0.316 mL | 0.632 mL | 0.7899 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Labdane-type diterpenes from Hedychium gardnerianum with potent cytotoxicity against human small cell lung cancer cells.[Pubmed:19960422]
Phytother Res. 2010 Jul;24(7):1009-13.
Seven labdane-type diterpenes, coronarin E, coronarin A, yunnancoronarin A, Yunnancoronarin B, hedyforrestin B, villosin, and hedyforrestin C were isolated from the rhizome of Hedychium gardnerianum and evaluated for cytotoxic activity against human small cell lung cancer (NCI-H187) and non-cancerous Vero cells. The results showed that villosin exhibited potent cytotoxic activity with IC(50) of 0.40 microM, which was higher than that of the drug ellipticine (IC(50) 1.79 microM). Moreover, ellipticine was very toxic to Vero cells (IC(50) 7.47 microM) whereas the toxicity of villosin was undetectable at concentration lower than 166.42 microM. The results have indicated that the lactone ring is essential for high cytotoxic activity and that the presence of a hydroxyl group at the 6 or 7 position causes decrease in activity. The very high cytotoxicity against the NCI-H187 cells and the exceptionally high selectivity index (>416) of villosin suggested that this compound may be used as a potential lead molecule for antitumor therapeutic development.
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