Zedoalactone ECAS# 1228391-67-0 |
Quality Control & MSDS
Package In Stock
Number of papers citing our products
| Cas No. | 1228391-67-0 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C15H22O4 | M.Wt | 266.37 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Zedoalactone E Dilution Calculator
Zedoalactone E Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.7542 mL | 18.7709 mL | 37.5418 mL | 75.0835 mL | 93.8544 mL |
| 5 mM | 0.7508 mL | 3.7542 mL | 7.5084 mL | 15.0167 mL | 18.7709 mL |
| 10 mM | 0.3754 mL | 1.8771 mL | 3.7542 mL | 7.5084 mL | 9.3854 mL |
| 50 mM | 0.0751 mL | 0.3754 mL | 0.7508 mL | 1.5017 mL | 1.8771 mL |
| 100 mM | 0.0375 mL | 0.1877 mL | 0.3754 mL | 0.7508 mL | 0.9385 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antiinflammation constituents from Curcuma zedoaroides.[Pubmed:30109745]
Phytother Res. 2018 Nov;32(11):2312-2320.
Curcuma zedoaroides, a Zingiberaceae species, has been used for snake bite antidote and wound care in Thailand. Seven compounds were isolated from the bioactive chloroform extract consisted of one new guaiane sesquiterpene lactone, 5-epiphaeocaulisin A (4) and one new diarylheptanoid, 1,2,3,5-tetrahydroxy-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl) heptane (7), together with five known guaiane-type sesquiterpene lactones including gweicurculactone (1), zedoalactone B (2), phaeocaulisin C (3), zedoalactone H (5), and Zedoalactone E (6). The antiinflammation was investigated on NO and TNF-alpha production using RAW264.7 cells. In addition, the expressions of genes involved in inflammation including iNOS, COX-2, and TNF-alpha were assessed. The results found that Compounds 1-7 presented their antiinflammation against NO production. The most potential effects were demonstrated on Compounds 1 and 7 with IC(50) of 27.3 and 32.6 muM, respectively. Although, Compounds 1 and 7 did not inhibit TNF-alpha production, their suppression on iNOS and COX-2 mRNA expression were revealed. These results support the ability of chloroform fraction, Compounds 1 and 7 on antiinflammation, whereas others exhibited moderate and mild effect.
