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Macrophylloside A

CAS# 179457-66-0

Macrophylloside A

Catalog No. BCX0323----Order now to get a substantial discount!

Product Name & Size Price Stock
Macrophylloside A: 5mg $1098 In Stock
Macrophylloside A: 10mg Please Inquire In Stock
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Quality Control of Macrophylloside A

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Chemical structure

Macrophylloside A

Chemical Properties of Macrophylloside A

Cas No. 179457-66-0 SDF Download SDF
PubChem ID N/A Appearance Powder
Formula C40H44O22 M.Wt 876.84
Type of Compound Iridoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Macrophylloside A Dilution Calculator

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Macrophylloside A Molarity Calculator

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Preparing Stock Solutions of Macrophylloside A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.1405 mL 5.7023 mL 11.4046 mL 22.8092 mL 28.5115 mL
5 mM 0.2281 mL 1.1405 mL 2.2809 mL 4.5618 mL 5.7023 mL
10 mM 0.114 mL 0.5702 mL 1.1405 mL 2.2809 mL 2.8511 mL
50 mM 0.0228 mL 0.114 mL 0.2281 mL 0.4562 mL 0.5702 mL
100 mM 0.0114 mL 0.057 mL 0.114 mL 0.2281 mL 0.2851 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Macrophylloside A

Metabolomics Combined with Multivariate Statistical Analysis for Screening of Chemical Markers between Gentiana scabra and Gentiana rigescens.[Pubmed:32182812]

Molecules. 2020 Mar 9;25(5):1228.

Gentianae Radix et Rhizome (Longdan in Chinese, GRR) in Chinese Pharmacopoeia is derived from the dried roots and rhizomes of Gentiana scabra and G. rigescens, that have long been used for heat-clearing and damp-drying in the medicinal history of China. However, the characterization of the chemical components of two species and the screening of chemical markers still remain unsolved. In current research, the identification and characterization of chemical components of two species was performed using ultra-high-performance liquid chromatography (UHPLC) coupled with linear ion trap-Orbitrap (LTQ-Orbitrap) mass spectrometry. Subsequently, the chemical markers of two species were screened based on metabolomics and multivariate statistical analysis. In total, 87 chemical constituents were characterized in G. scabra (65 chemical constituents) and G. rigescens (51 chemical constituents), with 29 common chemical constituents being discovered. Thereafter, 11 differential characteristic components which could differentiate the two species were designated with orthogonal partial least squares discriminant analysis (OPLS-DA) and random forest (RF) iterative modeling. Finally, seven characteristic components identified as (+)-syringaresinol, lutonarin, trifloroside, 4-O-beta-d-glu-trifloroside, 4''-O-beta-d-glucopyranosy1-6'-O-(4-O-beta-d-glucaffeoyl)-linearroside, Macrophylloside A and scabraside were selected as the chemical markers for the recognition of two Gentiana species. It was implied that the results could distinguish the GRR derived from different botanical sources, and also be beneficial in the rational clinical use of GRR.

Secoiridoid glycosides and an antifungal anthranilate derivative from Gentiana tibetica.[Pubmed:9611826]

Phytochemistry. 1998 Apr;47(7):1223-6.

Repetitive chromatography of the methanol extract of the roots of Gentiana tibetica afforded two new secoiridoid glycosides and a novel antifungal anthranilic acid derivative, together with beta-sitosterol, daucosterol, oleanolic acid, loganic acid, gentiopicroside, sweroside, 2'-(2,3-dihydroxybenzoyl)sweroside, trifloroside, rindoside and Macrophylloside A. The structures of the new products were determined mainly by spectroscopic methods as 8-hydroxy-10-hydrosweroside, isoMacrophylloside And ethyl N-docosanoylanthranilate. Ethyl N-docosanoylanthranilate inhibited the growth of the human pathogenic fungi Candida albicans and Aspergillus flavus. The taxonomic significance of the constituent is discussed briefly.

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