Inhibitor of Apoptosis
The inhibitor of apoptosis (IAP) family of proteins are major regulators of apoptosis through interaction with components of the apoptotic signaling cascades. Discovered in baculovirus, human homologs can be described as baculovirus IAP repeat containing (BIRC) proteins.
Products for Inhibitor of Apoptosis
- Cat.No. Product Name Information/Activity
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BCN2678
Embelin
Embelin is a cell-permeable benzoquinone compound that exhibits antitumor properties.
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BCC8042
UC 112
UC-112 is a novel potent IAP(Inhibitor of apoptosis) inhibitor; potently inhibit cell growth in two human melanoma (A375 and M14) and two human prostate (PC-3 and DU145) cancer cell lines(IC50=0.7-3.4 uM).
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BCN5984
Triptolide
Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory and antiproliferative effects. Triptolide is a NF-κB activation inhibitor.
