NTPDase

Ectonucleotidases (also known as NTPDases, Ecto-ATPases, ectonucleoside triphosphate diphosphohydrolase) are constitutively expressed ectoenzymes that hydrolyze extracellular nucleotides. There are four known major families of ectonucleotidases.

Products for NTPDase

  1. Cat.No. Product Name Information/Activity
  2. BCC7004 ARL 67156 trisodium salt ARL67156 trisodium salt is an inhibitor of ecto-ATPase. ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively. ARL 67156 trisodium salt chemical structure
  3. BCC7454 POM 1 Sodium metatungstate (POM-1) is a potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitor, with Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1, NTPDase 3 and NTPDase 2 respectively. Sodium metatungstate (POM-1) inhibits ATP breakdown but also blocks central synaptic transmission, an action independent of NTPDase inhibition. POM 1 chemical structure
  4. BCC7417 PSB 06126 1052089-16-3 PSB 06126 chemical structure
  5. BCC7416 PSB 069 78510-31-3 PSB 069 chemical structure

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