Casein Kinase 1
Casein kinase I (CK1) is a monomeric serine-threonine protein kinase with 7 isoforms: α , β , γ 1, γ 2, γ 3, δ and ε . CK1 is involved in many cellular processes including DNA repair, cell division, nuclear localization and membrane transport. Isoforms are also integral to development.
Products for Casein Kinase 1
- Cat.No. Product Name Information/Activity
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BCC5614
CKI 7 dihydrochloride
1177141-67-1
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BCC1508
D4476
D4476 is a potent, selective and cell-permeable inhibitor of casein kinase 1(CK1) with an IC50 value of 0.3 μM in vitro.
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BCC7726
(R)-DRF053 dihydrochloride
Dual cdk1/cdk5 inhibitor. Also inhibits CK1
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BCC4246
LH846
LH846 is a selective inhibitor of CKIδ, with an IC50 of 290 nM, and less potently inhibits CKIα and CKIε, with IC50s of 2.5 μM and 1.3 μM, respectively.
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BCC7904
PF 4800567 hydrochloride
1391052-28-0
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BCC1856
PF-670462
PF-670462 is a potent and selective inhibitor of casein kinase (CK1ε and CK1δ), with IC50s of 7.7 nM and 14 nM, respectively.
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BCC3968
TAK-715
TAK-715 is a p38 MAPK inhibitor for p38α with IC50 of 7.1 nM, 28-fold more selective for p38α over p38β, no inhibition to p38γ/δ, JNK1, ERK1, IKKβ, MEKK1 or TAK1.
