Protein Kinase G
Protein Kinase G (PKG) is a cyclic GMP-dependent protein serine/threonine kinase that phosphorylates a variety of biological targets. There are two subtypes of PKG: PKG1 and PKG2 and, due to alternative exon splicing, two isoforms of PKG1 - PKG1α and PKG1β .
Products for Protein Kinase G
- Cat.No. Product Name Information/Activity
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BCC7538
Rp-8-Br-PET-cGMPS
185246-32-6
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BCC8084
cGMP Dependent Kinase Inhibitor Peptide
82801-73-8
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BCC7006
KT 5823
KT5823, a selective the cGMP-dependent protein kinase (PKG) inhibitor with an Ki value of 0.23 μM, it also inhibits PKA and PKC with Ki values of 10 μM and 4 μM, respectively. KT5823 is a staurosporine-related protein kinase inhibitor, increases thyroid-stimulating hormone-induced (Na+/I- symporter) NIS expression, and iodide uptake in thyroid cells. KT5823 arrests cells after the G0/G1 boundary and causes increases in the levels of apoptotic DNA fragmentation.
