Kinesin
Kinesin superfamily proteins (KIFs) are motor proteins that convert chemical energy into mechanical force, typically by hydrolysis of ATP. They act upon microtubules to move vesicles and organelles from the cell centre to the periphery and cause the beating of flagella and cilia.
Products for Kinesin
- Cat.No. Product Name Information/Activity
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BCC2391
ARRY 520 trifluoroacetate
Potent and selective kinesin spindle protein (KSP) inhibitor; induces Mcl-1 degradation,ARRY-520 is a synthetic kinesin spindle protein (<b>KSP</b>) inhibitor with <b>IC<sub>50</sub></b> of 6 nM.
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BCC2509
Ispinesib (SB-715992)
Ispinesib is a specific inhibitor of kinesin spindle protein (KSP), with a Ki app of 1.7 nM.
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BCC7760
K858
K858 Racemic is an ATP-uncompetitive inhibitor of kinesin Eg5 with an IC50 of 1.3 μM.
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BCC7978
Paprotrain
Paprotrain is a cell-permeable inhibitor of the kinesin MKLP-2, inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM and shows a moderate inhibition activity on DYRK1A with an IC50 of 5.5 μM.
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BCC4559
SB743921
SB-743921 is a potent inhibitor of the mitotic kinesin KSP (Eg5), with a Ki of 0.1 nM.
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BCC2911
H-Cys(Trt)-OH
2799-07-7
