Calcium Binding Protein Modulator
Calcium binding proteins regulate the concentration of Ca2+ available as a second messenger in many signaling cascades. The most common calcium binding protein, calmodulin, is found in the cytoplasm, organelles or associated with plasma membranes in eukaryotic cells.
Products for Calcium Binding Protein Modulator
- Cat.No. Product Name Information/Activity
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BCC5900
CALP3
CALP3, a Ca2+-like peptide, is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels and pumps. CALP3 has the potential in controlling apoptosis in diseases such as AIDS or neuronal loss due to ischemia.
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BCC6625
A-7 hydrochloride
79127-24-5
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BCC7410
Calmidazolium chloride
Calmidazolium chloride (R 24571) is a calmodulin (CaMK) antagonist, antagonizing CaM-dependent phosphodiesterase and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase with IC50s of 0.15 and 0.35 μM, respectively. Also in anti-cancer research. Calmidazolium binds to CaMK with a Kd of 3 nM.
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BCC5898
CALP2
261969-04-4
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BCC5690
Camstatin
1002295-95-5
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BCC7303
CGS 9343B
Zaldaride maleate (CGS-9343B) is a potent, orally active and selective inhibitor of calmodulin. Zaldaride maleate (CGS-9343B) inhibits CaM (calmodulin)-stimulated cAMP phosphodiesterase activity, with an IC50 of 3.3 nM. Zaldaride maleate (CGS-9343B) prevents estrogen-induced transcription activation by ER, reversibly blocks voltage-activated Na+, Ca2+ and K+ currents in PC12 cells and inhibits nAChR.
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BCC6620
W-13 hydrochloride
88519-57-7
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BCC6621
W-5 hydrochloride
61714-25-8
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BCC6622
W-7 hydrochloride
61714-27-0
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BCC6623
W-9 hydrochloride
69762-85-2
