Cardiovascular System Research

The cardiovascular, or circulatory, system is a closed elastic circuit consisting of the heart, blood vessels (arteries, capillaries and veins) and the blood. The primary function is to pump oxygenated blood to the tissues throughout the body and reabsorb waste carbon dioxide for its removal. This function is performed by the use of pulmonary and systemic circulation.

Cardiovascular System Research Products Areas

Products for Cardiovascular System Research - Page 39

  1. Cat.No. Product Name Information/Activity
  2. BCC7671 Valinomycin Valinomycin (NSC 122023) is a cyclic depsipeptide antibiotic first isolated from Streptomyces fulvissimus, act as a potassium selective ionophore. Valinomycin (NSC 122023) inhibits lymphocyte proliferation by its effects on the cell membrane, and induces apoptosis in CHO cells. Valinomycin induces activation of PINK1 leading to Parkin Ser65 phosphorylation. Valinomycin chemical structure
  3. BCC4377 Amiodarone HCl Amiodarone hydrochloride is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with IC50 of 19.1 μM. Amiodarone HCl chemical structure
  4. BCC4497 Erastin Erastin is a ferroptosis inducer. Erastin binds and inhibits voltage-dependent anion channels (VDAC2/VDAC3). Erastin chemical structure
  5. BCC5076 Ibutilide Fumarate Ibutilide fumarate is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm. Ibutilide Fumarate chemical structure
  6. BCC5051 Lamotrigine Lamotrigine(BW430C) is a novel anticonvulsant drug for inhibition of 5-HT and sodium channel Target: Sodium Channel Lamotrigine stabilises presynaptic neuronal membranes by blockade of voltage-dependent sodium channels, thus preventing the release of excitatory neurotransmitters, particularly glutamate and aspartate [1]. Lamotrigine chemical structure
  7. BCC7327 LOE 908 hydrochloride 143482-60-4 LOE 908 hydrochloride chemical structure
  8. BCC6059 4,4-Pentamethylenepiperidine hydrochloride 1125-01-5 4,4-Pentamethylenepiperidine hydrochloride chemical structure
  9. BCC7863 Quinidine Quinidine is an antiarrhythmic agent for the treatment of abnormal heart rhythms and also malaria. Quinidine chemical structure
  10. BCC5288 TRO 19622 Olesoxime (TRO 19622) is a mitochondrial-targeted neuroprotective compound with mean EC50 value for increasing cell survival is 3.2±0.2 µM. TRO 19622 chemical structure
  11. BCC2512 Zonisamide Zonisamide is a 1,2 benzisoxazole derivative and the first agent of this chemical class to be developed as an antiepileptic drug. Zonisamide chemical structure

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