Vitamin D Receptor

Vitamin D receptors (VDRs) are members of the NR1I family, which also includes pregnane X receptors (PXR) and constitutive androstane receptors (CAR). They form heterodimers with retinoid X receptor family members, and are expressed in the intestine, thyroid and kidney.

Products for Vitamin D Receptor

Cat.No. Product Name Information/Activity
BCC4950 Calcitriol Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.
BCC4902 Doxercalciferol Doxercalciferol is a Vitamin D2 analog, acts as an activator of Vitamin D receptor, and prevent renal disease.
BCC1944 Seocalcitol Seocalcitol is a vitamin D analog, binds vitamin D receptor protein from human osteosarcoma MG-63 cells with Kd of 0.27 nM.
BCC1556 Ercalcitriol Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2.
BCC4962 Alfacalcidol Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis.
BCC4949 Calcifediol Calcifediol is a major circulating metabolite of vitamin D3, acting as a competitive inhibitor with an apparent Ki of 3.9 μM, suppresses PTH secretion and mRNA (ED50=2 nM).
BCC1444 Calcipotriol Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.
BCC1555 Ercalcidiol Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status.
BCC1975 Tacalcitol Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium.
BCN2186 Vitamin D3 Cholecalciferol(Vitamin D3) is a naturally occuring form of vitamin D; Reported that upon metabolic activation, Cholecalciferol induces cell differentiation and prevents proliferation of cancer cells.