Histamine H3 Receptor
Histamine H3 receptors are Gα i/o-protein-coupled receptors expressed at high levels on histaminergic neurons in the CNS, particularly in the basal ganglia, cortex and hippocampus. H3 receptors are thought to function as presynaptic autoreceptors.
Products for Histamine H3 Receptor
- Cat.No. Product Name Information/Activity
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BCC4530
Histamine 2HCl
Histamine dihydrochloride is an endogenous metabolite.
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BCC6768
Imetit dihydrobromide
Imetit dihydrobromide (VUF 8325 dihydrobromide) is a high affinity and potent agonist of histamine H3 and H4 receptors, with Ki values of 0.3 and 2.7 nM, respectively. Imetit mimics histamine effect in triggering a shape change in eosinophils (EC50=25 nM).
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BCC6853
Immepip dihydrobromide
164391-47-3
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BCC7524
Methimepip dihydrobromide
817636-54-7
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BCC5665
(R)-(-)-α-Methylhistamine dihydrobromide
(R)-(-)-α-Methylhistamine dihydrobromide is a potent and selective H3 histamine receptor agonist with a Kd of 50.3 nM. (R)-(-)-α-Methylhistamine dihydrobromide can cross the blood-brain barrier, and can enhance memory retention, attenuates memory impairment in rats.
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BCC6700
(S)-(+)-α-Methylhistamine dihydrobromide
75614-93-6
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BCC6701
Nα-Methylhistamine dihydrochloride
16503-22-3
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BCC7378
Proxyfan oxalate
177708-09-7
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BCC7963
A 331440 dihydrochloride
Selective H<sub>3</sub> antagonist
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BCC1863
Pitolisant hydrochloride
Pitolisant hydrochloride is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor (Ki=0.16 nM).
