(S)-(+)-α-Methylhistamine dihydrobromideH3 agonist, less active enantiomer CAS# 75614-93-6 |
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Quality Control & MSDS
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| Cas No. | 75614-93-6 | SDF | Download SDF |
| PubChem ID | 45073439 | Appearance | Powder |
| Formula | C6H13Br2N3 | M.Wt | 287 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble to 100 mM in water | ||
| Chemical Name | (2S)-1-(1H-imidazol-5-yl)propan-2-amine;dihydrobromide | ||
| SMILES | CC(CC1=CN=CN1)N.Br.Br | ||
| Standard InChIKey | RWHNAAABSGVRDT-XRIGFGBMSA-N | ||
| Standard InChI | InChI=1S/C6H11N3.2BrH/c1-5(7)2-6-3-8-4-9-6;;/h3-5H,2,7H2,1H3,(H,8,9);2*1H/t5-;;/m0../s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Less active enantiomer of H3 agonist R-(-)-α-methylhistamine; 120-fold less potent than R-(-) at H3. |
(S)-(+)-α-Methylhistamine dihydrobromide Dilution Calculator
(S)-(+)-α-Methylhistamine dihydrobromide Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.4843 mL | 17.4216 mL | 34.8432 mL | 69.6864 mL | 87.108 mL |
| 5 mM | 0.6969 mL | 3.4843 mL | 6.9686 mL | 13.9373 mL | 17.4216 mL |
| 10 mM | 0.3484 mL | 1.7422 mL | 3.4843 mL | 6.9686 mL | 8.7108 mL |
| 50 mM | 0.0697 mL | 0.3484 mL | 0.6969 mL | 1.3937 mL | 1.7422 mL |
| 100 mM | 0.0348 mL | 0.1742 mL | 0.3484 mL | 0.6969 mL | 0.8711 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Distribution, properties, and functional characteristics of three classes of histamine receptor.[Pubmed:2164693]
Pharmacol Rev. 1990 Mar;42(1):45-83.
It is clear from the preceding overview of histamine receptor pharmacology that research into the pharmacology of histamine receptors is at an exciting stage of development. The rapid advance of molecular biology should soon see the structural identification and cloning of all three of the major vertebrate histamine receptors. Further work will continue toward enhancing our understanding of the control by histamine of intracellular signaling via H1- and H2-receptors, and the rapid explosion of work on the H3-receptor should begin to unravel the mechanisms underlying its actions, perhaps via effects on ionic channels. The potential role of histamine as an intracellular second messenger raises exciting possibilities, as does the search for a histamine receptor analogous to the ligand-gated ion channel in the invertebrate nervous system.
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