Amyloid beta Peptide
Amyloid β (Aβ ) peptides are the major component of amyloid plaques found in the brains of Alzheimer's patients. Aβ is formed from the progressive cleavage of amyloid precursor protein (APP) by β - and γ -secretase. Two Aβ peptides are formed from APP degradation.
Products for Amyloid beta Peptide - Page 3
- Cat.No. Product Name Information/Activity
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BCC4541
Latrepirdine
Latrepirdine dihydrochloride is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors. Latrepirdine stimulates amyloid precursor protein (APP) catabolism and amyloid-β (Aβ) secretion.
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BCC6360
J 147
J-147 is an exceptionally potent, orally active, neuroprotective agent for cognitive enhancement. J-147 can readily pass the blood brain barrier (BBB). J-147 can inhibit monoamine oxidase B (MAO B) and the dopamine transporter with EC50 values of 1.88 μM and 0.649 μM, respectively. J-147 has potential for the treatment of Alzheimer’s disease (AD).
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BCC5984
K 114
872201-12-2
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BCC6113
LPYFD-NH2
700361-48-4
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BCC6331
Methoxy-X04
863918-78-9
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BCC7727
Tramiprosate
Tramiprosate is a small, orally-administered compound that binds to soluble Aβ and reduces amyloid aggregation and subsequent deposition target: Aβ In vitro: Tramiprosate provides neuroprotection against Aβ-induced neurotoxicity in neuronal and mouse organotypic hippocampal cultures, and reverses Aβ-induced long-term potentiation (LTP) inhibition in rat hippocampus, in part, through activation of β-aminobutyric acid A (GABA-A) receptors.
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BCC2514
Tranilast
Tranilast is an antiallergic agent.
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BCC5795
Y-29794 oxalate
146794-84-5
