Ryanodine Receptor
The ryanodine receptors (RyRs) are a family of Ca2+ channels that mediate the release of Ca2+ from intracellular Ca2+ storage organelles. Three RyR isoforms have been identified to date, RyR1, RyR2 and RyR3, roles of which include contraction, secretion and synaptic transmission.
Products for Ryanodine Receptor
- Cat.No. Product Name Information/Activity
-
BCN5807
Caffeine
58-08-2
-
BCC7808
NAADP tetrasodium salt
5502-96-5
-
BCC7079
Suramin hexasodium salt
Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor. Suramin sodium salt is a potent inhibitor of sirtuins: SirT1 (IC50=297 nM), SirT2 (IC50=1.15 μM), and SirT5 (IC50=22 μM). Suramin sodium salt is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC50=5 μM). Suramin sodium salt is an antitrypanosomal, anti-neoplastic and anti-angiogenic agent.
-
BCC6673
Dantrolene, sodium salt
14663-23-1
-
BCC7067
Ruthenium Red
11103-72-3
-
BCC5742
Ryanodine
Ryanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa.
