Nicotinic (α7) Receptor
Alpha 7 (α 7) is a subunit of the neuronal nicotinic receptor that can combine to form homomeric receptors. The α 7 nAChR is prominent in the hippocampus, found on GABAergic interneurons of stratum oriens and stratum radiatum, and on pyramidal neurones.
Products for Nicotinic (α7) Receptor - Page 2
- Cat.No. Product Name Information/Activity
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BCC7394
TC 1698 dihydrochloride
787587-06-8
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BCC7264
α-Bungarotoxin
11032-79-4
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BCC1047
COG 133
ApoE peptide fragment; <span class='symbol'>α</span>7 nAChR antagonist
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BCC5974
α-Conotoxin ImI
156467-85-5
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BCC6897
Methyllycaconitine citrate
112825-05-5
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BCC7028
MG 624
77257-42-2
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BCC4027
Tropisetron Hydrochloride
Tropisetron Hydrochloride (SDZ-ICS-930) is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.
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BCC1324
A-867744
A-867744 is a highly potent and selective type II positive allosteric modulator (PAM) of the alpha7 nicotinic acetylcholine receptors (nAChR) with an EC50 of 1.0 μM.
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BCC7788
CCMI
CCMI is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs. CCMI has potential in CNS diseases with cognitive dysfunction.
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BCC1251
Ivermectin
Ivermectin (MK-933) is a broad-spectrum anti-parasite medication used in humans most commonly to treat nematode infections such as onchocerciasis, as well as scabies and lice. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X4 and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import.
